A systematic review and meta-analysis of the efficacy and safety of N-acetylcysteine in preventing aminoglycoside-induced ototoxicity: implications for the treatment of multidrug-resistant TB

Katharina Kranzer; Wael F Elamin; Helen Cox; James A Seddon; Nathan Ford; Francis Drobniewski

doi:10.1136/thoraxjnl-2015-207245

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Tuberculosis

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A systematic review and meta-analysis of the efficacy and safety of N-acetylcysteine in preventing aminoglycoside-induced ototoxicity: implications for the treatment of multidrug-resistant TB

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	Abstract	Full	Pdf
Sep 2015	808	71	150
Oct 2015	596	65	96
Nov 2015	715	54	101
Dec 2015	251	26	46
Jan 2016	184	29	46
Feb 2016	134	43	54
Mar 2016	158	30	32
Apr 2016	203	28	31
May 2016	144	30	34
Jun 2016	110	28	28
Jul 2016	72	19	16
Aug 2016	95	21	21
Sep 2016	153	16	32
Oct 2016	142	21	20
Nov 2016	118	23	27
Dec 2016	74	17	17
Jan 2017	61	18	17
Feb 2017	88	32	31
Mar 2017	120	37	26
Apr 2017	84	23	16
May 2017	162	25	28
Jun 2017	81	26	11
Jul 2017	171	27	22
Aug 2017	124	12	8
Sep 2017	189	23	23
Oct 2017	175	22	9
Nov 2017	172	25	21
Dec 2017	142	14	12
Jan 2018	156	15	8
Feb 2018	243	11	12
Mar 2018	185	37	17
Apr 2018	199	33	22
May 2018	237	26	11
Jun 2018	253	18	14
Jul 2018	230	23	21
Aug 2018	269	32	17
Sep 2018	201	56	19
Oct 2018	188	131	31
Nov 2018	229	227	62
Dec 2018	160	158	30
Jan 2019	149	143	32
Feb 2019	181	176	35
Mar 2019	196	177	46
Apr 2019	125	118	46
May 2019	191	180	54
Jun 2019	121	116	36
Jul 2019	79	75	56
Aug 2019	136	112	77
Sep 2019	134	111	64
Oct 2019	131	102	87
Nov 2019	93	75	68
Dec 2019	100	88	42
Jan 2020	129	107	57
Feb 2020	189	168	60
Mar 2020	105	91	60
Apr 2020	78	78	50
May 2020	99	92	67
Jun 2020	111	99	60
Jul 2020	68	59	32
Aug 2020	93	79	57
Sep 2020	124	99	55
Oct 2020	132	117	57
Nov 2020	123	103	65
Dec 2020	93	88	53
Jan 2021	134	120	55
Feb 2021	132	114	49
Mar 2021	126	112	52
Apr 2021	162	147	60
May 2021	126	118	61
Jun 2021	104	105	37
Jul 2021	97	99	49
Aug 2021	71	68	49
Sep 2021	43	41	19
Oct 2021	116	102	55
Nov 2021	67	53	37
Dec 2021	92	62	49
Jan 2022	98	82	35
Feb 2022	119	103	35
Mar 2022	118	101	71
Apr 2022	109	97	55
May 2022	122	110	59
Jun 2022	73	69	43
Jul 2022	80	70	32
Aug 2022	109	87	46
Sep 2022	88	84	52
Oct 2022	131	117	46
Nov 2022	94	67	48
Dec 2022	59	55	30
Jan 2023	48	36	28
Feb 2023	87	81	29
Mar 2023	103	87	37
Apr 2023	72	48	58
May 2023	96	76	46
Jun 2023	129	121	33
Jul 2023	116	89	61
Aug 2023	108	97	48
Sep 2023	96	70	27
Oct 2023	127	104	33
Nov 2023	71	64	37
Dec 2023	66	62	38
Jan 2024	65	65	35
Feb 2024	50	50	34
Mar 2024	71	65	36
Total	14831	7523	4259

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