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BMJ Journals More

Online First

January 23, 2019

Editorial
What causes pneumonia in children who have had their jabs?

Gemma L Saint, Dan B Hawcutt, Paul S McNamara

doi: 10.1136/thoraxjnl-2018-212625
Respiratory research
Use of autologous ^99mTechnetium-labelled neutrophils to quantify lung neutrophil clearance in COPD

Nicola Tregay, Malcolm Begg, Anthony Cahn, Neda Farahi, Kathryn Povey, Sujith Madhavan, Rosalind Simmonds, Daniel Gillett, Chandra Solanki, Anna Wong, Joanna Maison, Mark Lennon, Glyn Bradley, Emily Jarvis, Marius de Groot, Fred Wilson, Judith Babar, A Michael Peters, Edith M Hessel, Edwin R Chilvers

doi: 10.1136/thoraxjnl-2018-212509

January 19, 2019

Editorial
Wandering out of the GWAS wilderness: a new pathway paradigm for complex disease genetics

Jeffrey Sturek, Imre Noth

doi: 10.1136/thoraxjnl-2018-212511
Cystic fibrosis
Secondhand smoke alters arachidonic acid metabolism and inflammation in infants and children with cystic fibrosis

Benjamin T Kopp, Rohan Thompson, Jeeho Kim, Robert Konstan, Alejandro Diaz, Bennett Smith, Chandra Shrestha, Lynette K Rogers, Don Hayes, Dmitry Tumin, Frederick W Woodley, Octavio Ramilo, Don B Sanders, Judith A Groner, Asuncion Mejias

doi: 10.1136/thoraxjnl-2018-211845
Chronic obstructive pulmonary disease
Cluster-randomised trial of a nurse-led advance care planning session in patients with COPD and their loved ones

Carmen H M Houben, Martijn A Spruit, Hans Luyten, Herman-Jan Pennings, Vivian E M van den Boogaart, Jacques P H M Creemers, Geertjan Wesseling, Emiel F M Wouters, Daisy J A Janssen

doi: 10.1136/thoraxjnl-2018-211943
Chest clinic
Clinical challenges in a patient with two BRAF V600E-mutated diseases

Ella Willenbacher, Wolfgang Willenbacher, Judith Loeffler-Ragg

doi: 10.1136/thoraxjnl-2018-212481
Lung cancer
Impact of organisation and specialist service delivery on lung cancer outcomes

Jana Bhavani Adizie, Aamir Khakwani, Paul Beckett, Richard Hubbard, Neal Navani, Susan V Harden, Ian Woolhouse

doi: 10.1136/thoraxjnl-2018-212588
Lung cancer
Early specialist palliative care on quality of life for malignant pleural mesothelioma: a randomised controlled trial

Fraser Brims, Samal Gunatilake, Iain Lawrie, Laura Marshall, Carole Fogg, Cathy Qi, Lorraine Creech, Nicola Holtom, Stephanie Killick, Bernard Yung, David Cooper, Louise Stadon, Peter Cook, Elizabeth Fuller, Julie Walther, Claire Plunkett, Andrew Bates, Carolyn Mackinlay, Anil Tandon, Nicholas A Maskell, Karen Forbes, Najib M Rahman, Stephen Gerry, Anoop J Chauhan on behalf of the RESPECT-Meso investigators

doi: 10.1136/thoraxjnl-2018-212380

January 12, 2019

Chest clinic
A rare cause of chronic cough

Lynn Decoster, Ann Van der Goten, Isabel Eerens, Karolien Goffin, Anja De Rycke

doi: 10.1136/thoraxjnl-2018-212435
Editorial
Hypocapnia, mitochondria and surfactant secretion

Beata Kosmider, Karim Bahmed, Steven Kelsen

doi: 10.1136/thoraxjnl-2018-212624
Critical care
Dead space ventilation promotes alveolar hypocapnia reducing surfactant secretion by altering mitochondrial function

Martina Kiefmann, Sascha Tank, Marc-Oliver Tritt, Paula Keller, Kai Heckel, Leonie Schulte-Uentrop, Cynthia Olotu, Sonja Schrepfer, Alwin E Goetz, Rainer Kiefmann

doi: 10.1136/thoraxjnl-2018-211864

January 10, 2019

Chronic obstructive pulmonary disease
Vitamin D to prevent exacerbations of COPD: systematic review and meta-analysis of individual participant data from randomised controlled trials

David A Jolliffe, Lauren Greenberg, Richard L Hooper, Carolien Mathyssen, Rachida Rafiq, Renate T de Jongh, Carlos A Camargo, Christopher J Griffiths, Wim Janssens, Adrian R Martineau

doi: 10.1136/thoraxjnl-2018-212092
Brief communication
Asthma admission rates and patterns of salbutamol and inhaled corticosteroid prescribing in England from 2013 to 2017

Sherif Gonem, Andrew Cumella, Matthew Richardson

doi: 10.1136/thoraxjnl-2018-212723
Lung cancer
The Chest Australia Trial: a randomised controlled trial of an intervention to increase consultation rates in smokers at risk of lung cancer

Jon D Emery, Sonya R Murray, Fiona M Walter, Andrew Martin, Stephen Goodall, Danielle Mazza, Emily Habgood, Yvonne Kutzer, David John Barnes, Peter Murchie

doi: 10.1136/thoraxjnl-2018-212506

January 07, 2019

Chronic obstructive pulmonary disease
Biomarkers and clinical outcomes in COPD: a systematic review and meta-analysis

Jilles M Fermont, Katya L Masconi, Magnus T Jensen, Renata Ferrari, Valéria A P Di Lorenzo, Jacob M Marott, Philipp Schuetz, Henrik Watz, Benjamin Waschki, Hana Müllerova, Michael I Polkey, Ian B Wilkinson, Angela M Wood

doi: 10.1136/thoraxjnl-2018-211855

January 04, 2019

Interstitial lung disease
Randomised, double-blind, placebo-controlled pilot trial of omeprazole in idiopathic pulmonary fibrosis

Prosenjit Dutta, Wendy Funston, Helen Mossop, Vicky Ryan, Rhys Jones, Rebecca Forbes, Shilpi Sen, Jeffrey Pearson, S Michael Griffin, Jaclyn A Smith, Christopher Ward, Ian A Forrest, A John Simpson

doi: 10.1136/thoraxjnl-2018-212102
Editorial
Does auto-PAP work in patients with acute quadriplegia and sleep-disordered breathing?

Abdulghani Sankari, M. Safwan Badr

doi: 10.1136/thoraxjnl-2018-212729

December 27, 2018

Lung cancer
Persisting new nodules in incidence rounds of the NELSON CT lung cancer screening study

Joan E Walter, Marjolein A Heuvelmans, Kevin ten Haaf, Rozemarijn Vliegenthart, Carlijn M van der Aalst, Uraujh Yousaf-Khan, Peter M A van Ooijen, Kristiaan Nackaerts, Harry J M Groen, Geertruida H De Bock, Harry J de Koning, Matthijs Oudkerk

doi: 10.1136/thoraxjnl-2018-212152

December 22, 2018

Chest clinic
Pulmonary inflammatory myofibroblastic tumour and IgG₄-related disease presenting with lower limb paralysis

Shuo Zhang, Shangzhu Zhang, Wen Zhang, Jia He, Juhong Shi, Xiaofeng Zeng

doi: 10.1136/thoraxjnl-2018-212692

December 14, 2018

Respiratory epidemiology
Effect of childhood pneumococcal conjugate vaccination on invasive disease in older adults of 10 European countries: implications for adult vaccination

Germaine Hanquet, Pavla Krizova, Palle Valentiner-Branth, Shamez N Ladhani, J Pekka Nuorti, Agnes Lepoutre, Jolita Mereckiene, Mirjam Knol, Brita A Winje, Pilar Ciruela, Maria Ordobas, Marcela Guevara, Eisin McDonald, Eva Morfeldt, Jana Kozakova, Hans-Christian Slotved, Norman K Fry, Hanna Rinta-Kokko, Emmanuelle Varon, Mary Corcoran, Arie van der Ende, Didrik F Vestrheim, Carmen Munoz-Almagro, Pello Latasa, Jesus Castilla, Andrew Smith, Birgitta Henriques-Normark, Robert Whittaker, Lucia Pastore Celentano, Camelia Savulescu on behalf of The SpIDnet/I-MOVE+ Pneumo Group

doi: 10.1136/thoraxjnl-2018-211767

December 11, 2018

Sleep
Positive airway pressure for sleep-disordered breathing in acute quadriplegia: a randomised controlled trial

David J Berlowitz, Rachel Schembri, Marnie Graco, Jacqueline M Ross, Najib Ayas, Ian Gordon, Bonne Lee, Allison Graham, Susan V Cross, Martin McClelland, Paul Kennedy, Pradeep Thumbikat, Cynthia Bennett, Andrea Townson, Timothy J Geraghty, Sue Pieri-Davies, Raj Singhal, Karen Marshall, Deborah Short, Andrew Nunn, Duncan Mortimer, Doug Brown, Robert J Pierce, Peter A Cistulli the COSAQ Collaborative

doi: 10.1136/thoraxjnl-2018-212319

December 07, 2018

Brief communication
Alleviating mechanical constraints to ventilation with heliox improves exercise endurance in adult survivors of very preterm birth

Joseph W Duke, Amy M Zidron, Igor M Gladstone, Andrew T Lovering

doi: 10.1136/thoraxjnl-2018-212346

November 29, 2018

Respiratory research
Holistic services for people with advanced disease and chronic breathlessness: a systematic review and meta-analysis

Lisa Jane Brighton, Sophie Miller, Morag Farquhar, Sara Booth, Deokhee Yi, Wei Gao, Sabrina Bajwah, William D-C Man, Irene J Higginson, Matthew Maddocks

doi: 10.1136/thoraxjnl-2018-211589

November 26, 2018

Pulmonary vasculature
Reduced plasma levels of small HDL particles transporting fibrinolytic proteins in pulmonary arterial hypertension

Lars Harbaum, Pavandeep Ghataorhe, John Wharton, Beatriz Jiménez, Luke S G Howard, J Simon R Gibbs, Jeremy K Nicholson, Christopher J Rhodes, Martin R Wilkins

doi: 10.1136/thoraxjnl-2018-212144

November 24, 2018

Lung cancer
5 protein-based signature for resectable lung squamous cell carcinoma improves the prognostic performance of the TNM staging

Elena Martínez-Terroba, Carmen Behrens, Jackeline Agorreta, Eduard Monsó, Laura Millares, Enriqueta Felip, Rafael Rosell, José Luis Ramirez, Ana Remirez, Wenceslao Torre, Ignacio Gil-Bazo, Miguel A Idoate, Juan P de-Torres, Ruben Pio, Ignacio I Wistuba, María J Pajares, Luis M Montuenga

doi: 10.1136/thoraxjnl-2018-212194
Brief communication
Hyperpolarised xenon magnetic resonance spectroscopy for the longitudinal assessment of changes in gas diffusion in IPF

Nicholas D Weatherley, Neil J Stewart, Ho-Fung Chan, Matthew Austin, Laurie J Smith, Guilhem Collier, Madhwesha Rao, Helen Marshall, Graham Norquay, Stephen A Renshaw, Stephen Mark Bianchi, Jim M Wild

doi: 10.1136/thoraxjnl-2018-211851

November 21, 2018

Brief communication
Smoking uptake in UK children: analysis of the UK Millennium Cohort Study

Anthony A Laverty, Filippos T Filippidis, David Taylor-Robinson, Christopher Millett, Andrew Bush, Nicholas S Hopkinson

doi: 10.1136/thoraxjnl-2018-212254

November 12, 2018

Tuberculosis
Predicting tuberculosis relapse in patients treated with the standard 6-month regimen: an individual patient data meta-analysis

Kamila Romanowski, Robert F Balshaw, Andrea Benedetti, Jonathon R Campbell, Dick Menzies, Faiz Ahmad Khan, James C Johnston

doi: 10.1136/thoraxjnl-2017-211120
Brief communication
Second round results from the Manchester ‘Lung Health Check’ community-based targeted lung cancer screening pilot

Phil A Crosbie, Haval Balata, Matthew Evison, Melanie Atack, Val Bayliss-Brideaux, Denis Colligan, Rebecca Duerden, Josephine Eaglesfield, Timothy Edwards, Peter Elton, Julie Foster, Melanie Greaves, Graham Hayler, Coral Higgins, John Howells, Klaus Irion, Devinda Karunaratne, Jodie Kelly, Zoe King, Judith Lyons, Sarah Manson, Stuart Mellor, Donna Miller, Amanda Myerscough, Tom Newton, Michelle O’Leary, Rachel Pearson, Julie Pickford, Richard Sawyer, Nick J Screaton, Anna Sharman, Maggi Simmons, Elaine Smith, Ben Taylor, Sarah Taylor, Anna Walsham, Angela Watts, James Whittaker, Laura Yarnell, Anthony Threlfall, Phil V Barber, Janet Tonge, Richard Booton

doi: 10.1136/thoraxjnl-2018-212547

November 01, 2018

Brief communication
Primary lung cancer in patients with previous malignancies: a nationwide study

Onno M Mets, Cornelia M Schaefer-Prokop, Pim A de Jong

doi: 10.1136/thoraxjnl-2018-211891

October 31, 2018

State of the art review
Natural killer cells in lung transplantation

Daniel R Calabrese, Lewis L Lanier, John R Greenland

doi: 10.1136/thoraxjnl-2018-212345

October 26, 2018

Brief communication
Effect of mandibular advancement therapy on inflammatory and metabolic biomarkers in patients with severe obstructive sleep apnoea: a randomised controlled trial

Sylvain Recoquillon, Jean-Louis Pépin, Bruno Vielle, Ramaroson Andriantsitohaina, Vanessa Bironneau, Frédérique Chouet-Girard, Bernard Fleury, François Goupil, Sandrine Launois, M Carmen Martinez, Nicole Meslier, Xuan-Lan Nguyen, Audrey Paris, Pascaline Priou, Renaud Tamisier, Wojciech Trzepizur, Frédéric Gagnadoux

doi: 10.1136/thoraxjnl-2018-212609

October 24, 2018

Brief communication
Predicting outcomes in primary spontaneous pneumothorax using air leak measurements

Rob J Hallifax, Magda Laskawiec-Szkonter, Najib M Rahman on behalf of The RAMPP Trial collaborators

doi: 10.1136/thoraxjnl-2018-212116

October 18, 2018

Respiratory infection
The contribution of viruses and bacteria to community-acquired pneumonia in vaccinated children: a case–control study

Mejbah Uddin Bhuiyan, Thomas L Snelling, Rachel West, Jurissa Lang, Tasmina Rahman, Caitlyn Granland, Camilla de Gier, Meredith L Borland, Ruth B Thornton, Lea-Ann S Kirkham, Chisha Sikazwe, Andrew C Martin, Peter C Richmond, David W Smith, Adam Jaffe, Christopher C Blyth

doi: 10.1136/thoraxjnl-2018-212096

October 12, 2018

Brief communication
Impact of an increase in the inhaled corticosteroid dose on blood eosinophils in asthma

Marek Lommatzsch, Maria Klein, Paul Stoll, Johann Christian Virchow

doi: 10.1136/thoraxjnl-2018-212233

October 09, 2018

Cystic fibrosis
Gaps in the evidence for treatment decisions in cystic fibrosis: a systematic review

Nicola Jane Rowbotham, Sherie Smith, Andrew P Prayle, Karen A Robinson, Alan Robert Smyth

doi: 10.1136/thoraxjnl-2017-210858
Brief communication
Incidence of primary graft dysfunction after lung transplantation is altered by timing of allograft implantation

Peter S Cunningham, Robert Maidstone, Hannah J Durrington, Rajamayier V Venkateswaran, Marcelo Cypel, Shaf Keshavjee, Julie E Gibbs, Andrew S Loudon, Chung-Wai Chow, David W Ray, John F Blaikley

doi: 10.1136/thoraxjnl-2018-212021

October 03, 2018

Respiratory epidemiology
Interactive effect between ATPase-related genes and early-life tobacco smoke exposure on bronchial hyper-responsiveness detected in asthma-ascertained families

Marie-Hélène Dizier, Patricia Margaritte-Jeannin, Lucile Pain, Chloé Sarnowski, Myriam Brossard, Hamida Mohamdi, Nolwenn Lavielle, Marie-Claude C Babron, Jocelyne Just, Mark Lathrop, Catherine Laprise, Emmanuelle Bouzigon, Florence Demenais, Rachel Nadif

doi: 10.1136/thoraxjnl-2018-211797

September 22, 2018

Brief communication
Sputum exosomes: promising biomarkers for idiopathic pulmonary fibrosis

Makon-Sébastien Njock, Julien Guiot, Monique A Henket, Olivier Nivelles, Marc Thiry, Franck Dequiedt, Jean-Louis Corhay, Renaud E Louis, Ingrid Struman

doi: 10.1136/thoraxjnl-2018-211897

September 18, 2018

Brief communication
Progranulin aggravates pulmonary immunopathology during influenza virus infection

Qin Luo, Xingxing Yan, Hongmei Tu, Yibing Yin, Ju Cao

doi: 10.1136/thoraxjnl-2018-211916

August 30, 2018

Brief communication
Automated O₂ titration improves exercise capacity in patients with hypercapnic chronic obstructive pulmonary disease: a randomised controlled cross-over trial

Isabelle Vivodtzev, Erwan L’Her, Gabrielle Vottero, Claire Yankoff, Renaud Tamisier, François Maltais, François Lellouche, Jean-Louis Pépin

doi: 10.1136/thoraxjnl-2018-211967

August 12, 2018

Sleep
Minimum important difference of the Epworth Sleepiness Scale in obstructive sleep apnoea: estimation from three randomised controlled trials

Sarah Crook, Noriane A Sievi, Konrad E Bloch, John R Stradling, Anja Frei, Milo A Puhan, Malcolm Kohler

doi: 10.1136/thoraxjnl-2018-211959

July 19, 2018

Cystic fibrosis
Impact of cystic fibrosis on birthweight: a population based study of children in Denmark and Wales

Daniela K Schlüter, Rowena Griffiths, Abdulfatah Adam, Ashley Akbari, Martin L Heaven, Shantini Paranjothy, Anne-Marie Nybo Andersen, Siobhán B Carr, Tania Pressler, Peter J Diggle, David Taylor-Robinson

doi: 10.1136/thoraxjnl-2018-211706

April 05, 2018

Critical care
Predicting risk of unplanned hospital readmission in survivors of critical illness: a population-level cohort study

Nazir I Lone, Robert Lee, Lisa Salisbury, Eddie Donaghy, Pamela Ramsay, Janice Rattray, Timothy S Walsh

doi: 10.1136/thoraxjnl-2017-210822

February 13, 2018

Brief communication
Implementing lung cancer screening: baseline results from a community-based ‘Lung Health Check’ pilot in deprived areas of Manchester

Phil A Crosbie, Haval Balata, Matthew Evison, Melanie Atack, Val Bayliss-Brideaux, Denis Colligan, Rebecca Duerden, Josephine Eaglesfield, Timothy Edwards, Peter Elton, Julie Foster, Melanie Greaves, Graham Hayler, Coral Higgins, John Howells, Klaus Irion, Devinda Karunaratne, Jodie Kelly, Zoe King, Sarah Manson, Stuart Mellor, Donna Miller, Amanda Myerscough, Tom Newton, Michelle O’Leary, Rachel Pearson, Julie Pickford, Richard Sawyer, Nick J Screaton, Anna Sharman, Maggi Simmons, Elaine Smith, Ben Taylor, Sarah Taylor, Anna Walsham, Angela Watts, James Whittaker, Laura Yarnell, Anthony Threlfall, Phil V Barber, Janet Tonge, Richard Booton

doi: 10.1136/thoraxjnl-2017-211377

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November 29, 2018

November 26, 2018

November 24, 2018

November 21, 2018

November 12, 2018

November 01, 2018

October 31, 2018

October 26, 2018

October 24, 2018

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