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- asthma
- COPD mechanisms
- COPD epidemiology
- COPD exacerbations
- COPD pharmacology
- exercise
- lung physiology
- sleep apnoea
- asthma mechanisms
- cough/mechanisms/pharmacology
- assisted ventilation
- emphysema
- pulmonary rehabilitation
- tobacco and the lung
We thank the correspondents for these kind and helpful comments.1 In adopting the Global Initiative on Obstructive Lung Disease (GOLD) classification of severity of airflow obstruction, the National Institute for Health and Clinical Excellence (NICE) guideline update has introduced consistency with international guidelines including those of the American Thoracic Society and the European Respiratory Society. The NICE guidelines note that this classification relates specifically to degrees of airflow obstruction which are arbitrary and may not be closely related to degrees of clinical severity in chronic obstructive pulmonary disease (COPD).2 The current use of the term ‘severe’ for airflow obstruction with forced expiratory volume in 1 s (FEV1)<50% in place of ‘moderate’ (NICE 2004) may also help to underline the potentially serious nature of the lung function …
Footnotes
Competing interests None.
Patient consent Obtained.
Provenance and peer review Not commissioned; internally peer reviewed.