Article Text

Download PDFPDF
Influence of pulmonary vascular disease and fibrosis on prognosis following closed mitral valvotomy
  1. Rowan Nicks,
  2. V. J. McGovern
  1. Department of Cardiothoracic Surgery and the Fairfax Institute of Pathology, Royal Prince Alfred Hospital, Sydney, Australia


    We have examined biopsies of the lingula of the upper lobe of the left lung from 85 patients undergoing mitral valvotomy and have correlated the presence of vascular changes and fibrosis of the lung tissue with pulmonary vascular resistance, the degree and type of mitral stenosis, and the duration of pulmonary symptoms. Factors which significantly affected the prognosis were high pulmonary artery pressures, high vascular resistance, and narrowing of the pulmonary arteries; but, above all, pulmonary fibrosis. The prognosis for patients with mitral incompetence was less favourable than for those without incompetence, especially if there was increased pulmonary vascular resistance and pulmonary hypertension with axis deviation in the electrocardiogram.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


    • 1 Delivered to the General Scientific Meeting, Royal Australasian College of Surgeons, Melbourne, June 1966