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Lung alert
Miscellaneous
IL6 and dendritic cells in allergic asthma
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  1. C E Fletcher
  1. C E Fletcher, MRes Biomedical Research, Imperial College, London SW7 2AZ, UK; claire.fletcher07{at}imperial.ac.uk

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    Interleukin (IL)6 production by antigen-presenting dendritic cells (DCs) is integral to the differentiation of T helper cells into T helper type Th1, Th2 and Th17 subsets. However, molecular mechanisms that regulate IL6 production in DCs are yet to be elucidated. Stimulation of bone marrow-derived dendritic cells with the allergen house dust mite (HDM)—which causes asthma in humans—or the mucosal …

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