Can inactivated Mycobacterium vaccae vaccine help protect HIV positive patients against tuberculosis? | Thorax

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Can inactivated Mycobacterium vaccae vaccine help protect HIV positive patients against tuberculosis?

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V L C White

Locum Consultant Chest Physician, Barts and the London NHS Trust, London, UK; veronica.white@bartsandthelondon.nhs.uk

https://doi.org/10.1136/thx.2003.la68

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▴ Vuola JM, Ristola MA, Cole B, et al. Immunogenicity of an inactivated mycobacterial vaccine for the prevention of HIV-associated tuberculosis: a randomized, controlled trial. AIDS2003;17:2351–5

Inactivated vaccines have better safety profiles than live vaccines in HIV positive subjects, and previous research has shown that immunological responses to non-tuberculous mycobacteria provide protection against tuberculosis (TB).

This study compared the response of both …