[BOOK][B] Der Experimentator: Immunologie

W Luttmann, K Bratke, M Küpper, D Myrtek - 2014 - books.google.com
Lieber EXPERIMENTATOR, seit der Erstauflage im Jahr 2004 ist nun die 4. Auflage des
Immuno-EXPERIMENTATORS erschienen. Das Werk präsentiert die methodische Vielfalt der …

Extracellular ATP triggers and maintains asthmatic airway inflammation by activating dendritic cells

…, F Muskens, HC Hoogsteden, W Luttmann… - Nature medicine, 2007 - nature.com
Extracellular ATP serves as a danger signal to alert the immune system of tissue damage by
acting on P2X or P2Y receptors. Here we show that allergen challenge causes acute …

Alternatively activated alveolar macrophages in pulmonary fibrosis—mediator production and intracellular signal transduction

…, F Kollert, KMY Engel, J Dentler, W Luttmann… - Clinical …, 2010 - Elsevier
Activated macrophages have been characterized as M1 and M2 according to their inflammatory
response pattern. Here we analyzed the M2 marker expression and intracellular signal …

Neurotrophins are increased in bronchoalveolar lavage fluid after segmental allergen provocation

…, P Julius, M Lommatzsch, W Luttmann… - American journal of …, 1998 - atsjournals.org
The mechanisms linking inflammation and airway hyperresponsiveness in allergic
bronchial asthma are still not completely defined. Since neurotrophic factors increase nerve …

Human peritoneal mesothelial cells synthesize interleukin-6: induction by IL-1β and TNFα

N Topley, A Jörres, W Luttmann, MM Petersen… - Kidney international, 1993 - Elsevier
Human peritoneal mesothelial cells synthesize interleukin-6: Induction by IL-1β and TNFα.
Recent studies have demonstrated increased levels of IL-6 in the peritoneal cavity during …

Differential expression of human granzymes A, B, and K in natural killer cells and during CD8+ T cell differentiation in peripheral blood

…, B Bade, JC Virchow Jr, W Luttmann - European journal of …, 2005 - Wiley Online Library
NK cells and cytotoxic T lymphocytes can induce apoptosis in virus‐infected and transformed
target cells via the granule exocytosis pathway. The key components of the cytolytic …

Endobronchial secretion of interleukin-13 following local allergen challenge in atopic asthma: relationship to interleukin-4 and eosinophil counts

…, H Matthys, JC Virchow, W Luttmann - European …, 1996 - Eur Respiratory Soc
We investigated the secretion of interleukin (IL)-13 into the airways in 10 mild allergic asthmatics
by employing local allergen challenge, and compared the data both to IL-4 levels and …

The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 are survival and activation factors for eosinophils in …

…, S Schmidt, N Krug, W Luttmann… - The Journal of …, 2003 - rupress.org
Neurotrophins (nerve growth factor [NGF], brain-derived neurotrophic factor [BDNF], neurotrophin
[NT]-3, and NT-4) have been observed in elevated concentrations in allergic diseases. …

Th1 cytokine pattern in sarcoidosis is expressed by bronchoalveolar CD4+ and CD8+ T cells

…, H Hamm, H Matthys, W Luttmann… - Clinical & …, 2000 - academic.oup.com
The pathogenesis of pulmonary sarcoidosis has been related to an increased production of
Th1-like cytokines. However, cytokine expression in sarcoidosis has not been systematically …

Dendritic cell subsets in human bronchoalveolar lavage fluid after segmental allergen challenge

…, P Julius, M Kuepper, HD Kleine, W Luttmann… - Thorax, 2007 - thorax.bmj.com
Background: Dendritic cells control pulmonary immune reactions. Characteristics of dendritic
cells in human bronchoalveolar lavage fluid (BALF) after allergen challenge are unknown. …