Aerosol administration of antipseudomonal antibiotics is commonly used in cystic fibrosis.
However, its contribution to the improvement of lung function, infection and quality of life is not …

The aim of the present study was to perform a proof of principle study with a new colistin dry
powder inhalation system in six healthy volunteers and five patients with cystic fibrosis. All …

Objectives Selective oropharyngeal decontamination (SOD) and selective decontamination
of the digestive tract (SDD) are associated with improved outcomes among patients in …

Acute exacerbations of Pseudomonas aeruginosa lung infections were treated with ceftazidime
by continuous infusion in 17 adult patients with cystic fibrosis at home. Ceftazidime was …

Background Recently the influence of the upper airways (UAW) on the general health of a
patient with Cystic Fibrosis (CF) has been acknowledged. Surprisingly the microbiology of the …

This study was performed to determine the clinical pharmacokinetics of tobramycin in six
patients with cystic fibrosis (CF) after inhalation of 600 mg. Tobramycin was administered with …

BACKGROUND: Cross-infection of Pseudomonas aeruginosa has been reported to occur at
holiday camps for children with Cystic Fibrosis (CF) with varying frequency. The study …

Objectives The CLSI recommends a fixed 2 : 1 ratio of co-amoxiclav for broth microdilution
susceptibility testing of Enterobacteriaceae, while EUCAST recommends a fixed 2 mg/L …

Objectives The objective of this study was to determine time trends in the rate of Gram-positive
cocci in 42 Dutch ICUs that continuously used or did not use selective oropharyngeal …

Data on the pharmacokinetics of antibiotics after inhalation are limited. The aim of this pilot
study was to assess the pharmacokinetics of tobramycin under optimalized and standardized …