Methods This paper arose from an extensive literature review undertaken in developing the
Canadian Healthy Infant Longitudinal Development (CHILD) study, a multicentre national …

From asthma and heart disease to diabetes and obesity, the human microbiome plays a role
in the pathogenesis of each chronic health condition plaguing today's society. Recent work …

Background Pre-school children spend an average of two-hours daily using screens. We
examined associations between screen-time on pre-school behavior using data from the …

Background Early-life exposure to household pets has the capacity to reduce risk for
overweight and allergic disease, especially following caesarean delivery. Since there is some …

Importance Maternal overweight, which often results in cesarean delivery, is a strong risk
factor for child overweight. Little is known about the joint contribution of birth mode and …

Background Childhood asthma incidence is decreasing in some parts of Europe and North
America. Antibiotic use in infancy has been associated with increased asthma risk. In the …

Rationale: Factors predicting the development of wheeze may differ between sexes and
between childhood and adolescence. Methods: A New Zealand birth cohort of 1,037 children …

Background The atopic march describes the progression from atopic dermatitis during
infancy to asthma and allergic rhinitis in later childhood. In a Canadian birth cohort we …

Dysbiosis of gut microbiota has been retrospectively linked to autism spectrum disorders but
the temporal association between gut microbiota and early neurodevelopment in healthy …

BACKGROUND. A recurring epidemic of asthma exacerbations in children occurs annually
in September in North America when school resumes after summer vacation. OBJECTIVE. …