[HTML][HTML] LAMP1 targeting of the large T antigen of Merkel cell polyomavirus results in potent CD4 T cell responses and tumor inhibition
C Buchta Rosean, EC Leyder, J Hamilton… - Frontiers in …, 2023 - frontiersin.org
Introduction Most cases of Merkel cell carcinoma (MCC), a rare and highly aggressive type
of neuroendocrine skin cancer, are associated with Merkel cell polyomavirus (MCPyV) …
of neuroendocrine skin cancer, are associated with Merkel cell polyomavirus (MCPyV) …
Lack of association between adult asthma and the tumour necrosis factor alpha-308 polymorphism gene
R Louis, E Leyder, M Malaise… - European Respiratory …, 2000 - Eur Respiratory Soc
Tumour necrosis factor (TNF)alpha is a cytokine endowed with potent inflammatory properties
that may contribute to airway inflammation in asthma. It has previously been shown that …
that may contribute to airway inflammation in asthma. It has previously been shown that …
[PDF][PDF] Controllable self-replicating RNA vaccine delivered intradermally elicits predominantly cellular immunity
T Amano, H Yu, M Amano, E Leyder, M Badiola, P Ray… - IScience, 2023 - cell.com
Intradermal delivery of self-replicating RNA (srRNA) is a promising vaccine platform. We
have developed an srRNA that functions optimally at around 33C (skin temperature) and is …
have developed an srRNA that functions optimally at around 33C (skin temperature) and is …
[PDF][PDF] Homer1a regulates Shank3 expression and underlies behavioral vulnerability to stress in a model of Phelan-McDermid syndrome
…, LN Learman, MA Bangash, T Melnikova, E Leyder… - Cell Reports, 2021 - cell.com
Mutations of SHANK3 cause Phelan-McDermid syndrome (PMS), and these individuals can
exhibit sensitivity to stress, resulting in behavioral deterioration. Here, we examine the …
exhibit sensitivity to stress, resulting in behavioral deterioration. Here, we examine the …
Depression-related phenotypes at early stages of Aβ and tau accumulation in inducible Alzheimer's disease mouse model: Task-oriented and concept-driven …
E Leyder, P Suresh, R Jun, K Overbey… - Behavioural brain …, 2023 - Elsevier
… Dynamics of the percentage of time spent within the central zone is shown in E for both
sexes, and for male and female groups separately in F. The number of cases per group is noted …
sexes, and for male and female groups separately in F. The number of cases per group is noted …
CloudMach: cloud computing application performance improvement through machine learning
MA Sharkh, Y Xu, E Leyder - 2020 IEEE Canadian Conference …, 2020 - ieeexplore.ieee.org
Cloud computing is rapidly becoming the standard through which enterprises of all sizes
fulfill their computing infrastructure demands. This work aims at exploring the impact that …
fulfill their computing infrastructure demands. This work aims at exploring the impact that …
Changes in social, sexual, and hedonic behaviors in rats in response to stress and restoration by a negative allosteric modulator of α5-subunit containing GABA …
AM Bailey, A Barrett, L Havens, E Leyder… - Behavioural Brain …, 2023 - Elsevier
… (e) There was a negative correlation between aggressive behaviors in the agonistic behavioral
measurement and dominance scores in the tube test following CRS. (f) One injection of L-…
measurement and dominance scores in the tube test following CRS. (f) One injection of L-…
[HTML][HTML] Loss of GDE2 leads to complex behavioral changes including memory impairment
D Daudelin, A Westerhaus, N Zhang, E Leyder… - Behavioral and Brain …, 2024 - Springer
… E, F Total percent distance traveled in the open arms of the plus maze (E) and its dynamics
(F) at 7 months. No effect of genotype or its interactions were detected (ANOVA, Ps > 0.05). G …
(F) at 7 months. No effect of genotype or its interactions were detected (ANOVA, Ps > 0.05). G …
[HTML][HTML] A Phase I/II Clinical Trial of Intradermal, Controllable Self-Replicating Ribonucleic Acid Vaccine EXG-5003 against SARS-CoV-2
…, M Koga, MSH Ko, T Amano, H Yu, M Amano, E Leyder… - Vaccines, 2023 - mdpi.com
mRNA vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
have played a key role in reducing morbidity and mortality from coronavirus disease 2019 (…
have played a key role in reducing morbidity and mortality from coronavirus disease 2019 (…
A phase I/II clinical trial of intradermal, controllable self-replicating RNA vaccine EXG 5003 against SARS-CoV-2
…, M Koga, MSH Ko, T Amano, H Yu, M Amano, E Leyder… - medRxiv, 2023 - medrxiv.org
mRNA vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
have played a key role in reducing morbidity and mortality from coronavirus disease 2019 (…
have played a key role in reducing morbidity and mortality from coronavirus disease 2019 (…