[HTML][HTML] The world federation of ADHD international consensus statement: 208 evidence-based conclusions about the disorder
Background Misconceptions about ADHD stigmatize affected people, reduce credibility of
providers, and prevent/delay treatment. To challenge misconceptions, we curated findings …
providers, and prevent/delay treatment. To challenge misconceptions, we curated findings …
[PDF][PDF] The biogenesis, functions, and challenges of circular RNAs
Covalently closed circular RNAs (circRNAs) are produced by precursor mRNA back-splicing
of exons of thousands of genes in eukaryotes. circRNAs are generally expressed at low …
of exons of thousands of genes in eukaryotes. circRNAs are generally expressed at low …
[HTML][HTML] An expanded view of complex traits: from polygenic to omnigenic
A central goal of genetics is to understand the links between genetic variation and disease.
Intuitively, one might expect disease-causing variants to cluster into key pathways that drive …
Intuitively, one might expect disease-causing variants to cluster into key pathways that drive …
The developmental transcriptome of Drosophila melanogaster
Drosophila melanogaster is one of the most well studied genetic model organisms;
nonetheless, its genome still contains unannotated coding and non-coding genes …
nonetheless, its genome still contains unannotated coding and non-coding genes …
[HTML][HTML] A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a respiratory
disease called coronavirus disease 2019 (COVID-19), the spread of which has led to a …
disease called coronavirus disease 2019 (COVID-19), the spread of which has led to a …
[HTML][HTML] SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19
S Zhang, Y Liu, X Wang, L Yang, H Li, Y Wang… - Journal of hematology & …, 2020 - Springer
Background Critically ill patients diagnosed with COVID-19 may develop a pro-thrombotic
state that places them at a dramatically increased lethal risk. Although platelet activation is …
state that places them at a dramatically increased lethal risk. Although platelet activation is …
A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for …
Background Quantification of the disease burden caused by different risks informs
prevention by providing an account of health loss different to that provided by a disease-by …
prevention by providing an account of health loss different to that provided by a disease-by …
[HTML][HTML] A marker for Stevens–Johnson syndrome
WH Chung, SI Hung, HS Hong, MS Hsih, LC Yang… - Nature, 2004 - nature.com
Stevens–Johnson syndrome and the related disease toxic epidermal necrolysis are life-
threatening reactions of the skin to particular types of medication,,. Here we show that there …
threatening reactions of the skin to particular types of medication,,. Here we show that there …
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus
JW Han, HF Zheng, Y Cui, LD Sun, DQ Ye, Z Hu… - Nature …, 2009 - nature.com
We performed a genome-wide association study (GWAS) of systemic lupus erythematosus
(SLE) in a Chinese Han population by genotyping 1,047 cases and 1,205 controls using …
(SLE) in a Chinese Han population by genotyping 1,047 cases and 1,205 controls using …
[HTML][HTML] The Genomes of Oryza sativa: A History of Duplications
We report improved whole-genome shotgun sequences for the genomes of indica and
japonica rice, both with multimegabase contiguity, or almost 1,000-fold improvement over …
japonica rice, both with multimegabase contiguity, or almost 1,000-fold improvement over …