We present an extensive review of the literature to date pertaining to the rationale for using a
spacer/valved holding chamber (VHC) to deliver inhaled therapy from a pressurised …

Inhaled medication is the cornerstone of the pharmacological treatment of patients with
asthma and COPD. The major two classes of inhaled medication include corticosteroids …

For patients with COPD, inhalation is the preferred route of administration of respiratory
drugs for both maintenance and acute treatment. Numerous inhaler types and devices have …

To identify the site and cause of airflow limitation in patients with parkinsonism, we tested
pulmonary function in 27 patients with extrapyramidal disorders. In 24 patients, an abnormal …

Currently, no reliable data are available on the volume or on the cellular content of pleural
fluid in normal humans. In analogy with bronchoalveolar lavage (a technique enabling …

Patients referred for treatment of tracheal stenosis typically are asymptomatic until critical
narrowing of the airway occurs, which then requires immediate intervention. To understand …

It has been shown that structural changes in small airways of smokers with average smoking
histories greater than 35 pack-years could be reflected in the single-breath washout test …

Study objectives To evaluate the use of the FEV 1/forced expiratory volume at 6 s of
exhalation (FEV 6) ratio and FEV 6 as an alternative for FEV 1/FVC and FVC in the detection …

Verbanck, S., D. Schuermans, A. Van Muylem, M. Paiva, M. Noppen, and W. Vincken.
Ventilation distribution during histamine provocation. J. Appl. Physiol. 83 (6): 1907–1916 …

OBJECTIVE: To evaluate the retail sales of pressurised metered-dose inhalers (pMDIs), dry-
powder inhalers (DPIs) and liquids for nebulisation in 16 European countries. METHODS …