Gastro-oesophageal reflux and gastric aspiration in lung transplant patients with or without chronic rejection

K Blondeau, V Mertens… - European …, 2008 - Eur Respiratory Soc
Acid gastro-oesophageal reflux (GOR) and gastric aspiration have been labelled as risk
factors for chronic rejection bronchiolitis obliterans syndrome (BOS) after lung …

Evaluation of oesophageal mucosa integrity by the intraluminal impedance technique

R Farré, K Blondeau, D Clement, M Vicario, L Cardozo… - Gut, 2011 - gut.bmj.com
Background Oesophageal intraluminal impedance is currently used for assessment of reflux
in gastro-oesophageal reflux disease (GORD). Oesophageal mucosa integrity may have a …

Short exposure of oesophageal mucosa to bile acids, both in acidic and weakly acidic conditions, can impair mucosal integrity and provoke dilated intercellular spaces

R Farre, H van Malenstein, R De Vos, K Geboes… - Gut, 2008 - gut.bmj.com
Background: Severe duodeno-gastro-oesophageal reflux (DGOR) is a risk factor for
oesophagitis and Barrett's oesophagus. Patients with non-erosive reflux disease (NERD) …

Acid and weakly acidic solutions impair mucosal integrity of distal exposed and proximal non-exposed human oesophagus

R Farré, F Fornari, K Blondeau, M Vieth, R De Vos… - Gut, 2010 - gut.bmj.com
Background Oesophageal mucosa dilated intercellular spaces (DIS) may be important for
symptom perception in non-erosive reflux disease (NERD). Patients with NERD might have …

Improved diagnosis of gastro‐oesophageal reflux in patients with unexplained chronic cough

K Blondeau, LJ Dupont, V Mertens… - Alimentary …, 2007 - Wiley Online Library
Background Symptoms, oesophageal pHmetry and proton pump inhibitor treatment are
used for diagnosing gastro‐oesophageal reflux‐related cough. Weakly acidic reflux is now …

Gastro-oesophageal reflux and aspiration of gastric contents in adult patients with cystic fibrosis

K Blondeau, LJ Dupont, V Mertens, G Verleden… - Gut, 2008 - gut.bmj.com
Background: Gastro-oesophageal reflux (GOR) is increased in cystic fibrosis (CF), but its
prevalence, characteristics, association with gastric aspiration and respiratory impact are not …

Microscopic vascular invasion is the most relevant prognosticator after radical nephrectomy for clinically nonmetastatic renal cell carcinoma

H Van Poppel, H Vandendriessche, K Boel… - The Journal of …, 1997 - Elsevier
PURPOSE: Although many factors have been considered to predict the outcome after
radical nephrectomy, renal cell carcinoma continues to behave unpredictably. In a …

Azithromycin reduces gastroesophageal reflux and aspiration in lung transplant recipients

V Mertens, K Blondeau, A Pauwels, R Farre… - Digestive diseases and …, 2009 - Springer
Azithromycin (AZI) is a macrolide antibiotic that improves lung function in lung transplant
recipients (LTx). Gastroesophageal reflux (GER) has been implicated in the pathogenesis of …

Bile acids in sputum and increased airway inflammation in patients with cystic fibrosis

A Pauwels, A Decraene, K Blondeau, V Mertens… - Chest, 2012 - Elsevier
Background Up to 80% of patients with cystic fibrosis (CF) may have increased
gastroesophageal reflux and aspiration of duodenogastric contents into the lungs. We aimed …

The impact of traffic air pollution on bronchiolitis obliterans syndrome and mortality after lung transplantation

TS Nawrot, R Vos, L Jacobs, SE Verleden, S Wauters… - Thorax, 2011 - thorax.bmj.com
Background Approximately half of all patients who underwent a lung transplantation suffer
from bronchiolitis obliterans syndrome (BOS), the clinical correlate of chronic rejection …