Malignant pleural effusions are a common clinical problem in patients with neoplastic
disease. In one post mortem series, malignant effusions were found in 15% of patients who …

The aging of the population in the United States and throughout the developed world has
increased morbidity and mortality attributable to lung disease, while the morbidity and …

Although infectious, inflammatory and neoplastic diseases frequently involve the pleural
space and walls, little is known about the immunological and molecular mechanisms …

Idiopathic pulmonary fibrosis (IPF) is a disease with relentless course and limited
therapeutic options. Nintedanib (BIBF-1120) is a multiple tyrosine kinase inhibitor recently …

Eighteen patients with lupus erythematosus (LE) and pleural effusions were evaluated.
Fourteen patients had lupus pleuritis and four had pleural effusions of other etiologies. All …

Chronic inflammation involving both innate and adaptive immune cells is implicated in the
pathogenesis of asthma. Intercellular communication is essential for driving and resolving …

The expression of smooth muscle actin-α (SMA-α) by fibroblasts defines phenotypic
transition to myofibroblasts and is a primary contributor to contractile force generation by …

Pleural effusions secondary to various diseases are associated with the presence of
different inflammatory cells. The role of selective chemotactic cytokines in the recruitment of …

Pleurodesis aims to achieve a symphysis between parietal and visceral pleural surfaces, in
order to prevent accumulation of fluid or air in the pleural space. Its major indications are …

The mechanisms by which environmental exposures contribute to the pathogenesis of lung
fibrosis are unclear. Here, we demonstrate an increase in cadmium (Cd) and carbon black …