Background A common promoter polymorphism (rs35705950) in MUC5B, the gene
encoding mucin 5B, is associated with idiopathic pulmonary fibrosis. It is not known whether …

Importance Interstitial lung abnormalities have been associated with lower 6-minute walk
distance, diffusion capacity for carbon monoxide, and total lung capacity. However, to our …

Rationale: The relationship between the development and/or progression of interstitial lung
abnormalities (ILA) and clinical outcomes has not been previously investigated. Objectives …

Rationale: Interstitial lung abnormalities (ILA) are radiologic abnormalities on chest
computed tomography scans that have been associated with an early or mild form of …

The invention of hyperpolarized (HP) noble gas MRI using helium-3 (3 He) or xenon-129
(129 Xe) has provided a new method to evaluate lung function. Using HP 3 He or 129 Xe for …

Objective Interstitial lung disease (ILD) is a relatively common extraarticular manifestation of
rheumatoid arthritis (RA) that contributes significantly to disease burden and excess …

Purpose To evaluate the sensitivity, specificity, and severity of chest radiographs and chest
CT scans over time in patients confirmed positive for COVID-19 and those confirmed …

Rationale: Interstitial lung abnormalities (ILAs) are associated with the highest genetic risk
locus for idiopathic pulmonary fibrosis (IPF); however, the extent to which there are unique …

Methods We retrospectively identified a cohort of 424 patients who had undergone lung
nodule resection, had a chest CT scan within 3 months before surgery, and had no history of …

Rationale: Galectin-3 (Gal-3) has been implicated in the development of pulmonary fibrosis
in experimental studies, and Gal-3 levels have been found to be elevated in small studies of …