DNA amplification by the polymerase chain reaction to detect sub-clinical Pneumocystis carinii colonization in HIV-positive and HIV-negative male homosexuals with …

TR Leigh, HO Kangro, BG Gazzard, DJ Jeffries… - Respiratory …, 1993 - Elsevier
Pneumocystis carinii colonization was studied in 90 men using the polymerase chain
reaction. These comprised ten heterosexual controls; ten HIV-seronegative homosexual …

[HTML][HTML] Viral pneumonia

AM Freeman, TR Leigh Jr - 2018 - europepmc.org
Objectives: Describe the most common pathogens associated with viral pneumonia. Outline
the typical presentation of a patient with viral pneumonia. Identify the type of viral pneumonia …

Sputum induction for diagnosis of Pneumocystis carinii pneumonia

TR Leigh, C Hume, B Gazzard, P Parsons, OAN Husain… - The Lancet, 1989 - Elsevier
Abstract 51 patients infected with the human immunodeficiency virus (HIV) and with
suspected Pneumocystis carinii pneumonia underwent sputum induction. Sputum …

Comparison of DNA amplification and immunofluorescence for detecting Pneumocystis carinii in patients receiving immunosuppressive therapy

TR LEIGH, ANNE WAKEFIELD, SE PETERS… - …, 1992 - journals.lww.com
Two studies were performed to compare the sensitivity of DNA amplification with
immunofluorescence for the detection of Pneumocyatis carinii in asymptomatic normal and …

Serum titres of Pneumocystis carinii antibody in health care workers caring for patients with AIDS.

TR Leigh, MJ Millett, B Jameson, JV Collins - Thorax, 1993 - thorax.bmj.com
BACKGROUND--Pneumocystis carinii pneumonia was thought to occur from reactivation of
latent infection, but recent studies with the polymerase chain reaction have failed to detect P …

AIDS and the lung. 5--Tests giving an aetiological diagnosis in pulmonary disease in patients infected with the human immunodeficiency virus.

RF Miller, TR Leigh, JV Collins, DM Mitchell - Thorax, 1990 - ncbi.nlm.nih.gov
The use of non-invasive tests in the evaluation of pulmonary disease in patients with AIDS is
reviewed in the accompanying article in this series (p57'). Although non-invasive tests are …

Quantitative and qualitative comparison of DNA amplification by PCR with immunofluorescence staining for diagnosis of Pneumocystis carinii pneumonia.

TR Leigh, BG Gazzard, A Rowbottom… - Journal of clinical …, 1993 - jcp.bmj.com
AIM: To compare the results of DNA amplification by the polymerase chain reaction (PCR)
with immunofluorescence staining for detecting Pneumocystis carinii in bronchoalveolar …

Effect of sputum induction on arterial oxygen saturation and spirometry in HIV-infected patients

TR Leigh, K Kirby, BG Gazzard… - European Respiratory …, 1994 - Eur Respiratory Soc
We wanted to study the effect of sputum induction on forced expiratory volume in one
second (FEV1) and on oxygen saturation in normal controls, asymptomatic human …

Internal knotting of a guidewire: a complication of subclavian vein cannulation

TR Leigh, LR Baker, WR Cattell - Nephron, 1987 - scholar.archive.org
Dear Sir, The complications of subclavian vein cannulation are well recognised [1]. We have
recently encountered a previously unreported complication. A 46-year-old lady who had …

Performance characteristics of the DeVilbiss Ultraneb 99 ultrasonic nebuliser with reference to use in sputum induction

TR Leigh, T Nazir, J Wiggins, D Ganderton… - International journal of …, 1991 - Elsevier
Abstract The DeVilbiss Ultraneb 99 ultrasonic nebuliser is frequently used for sputum
induction in AIDS patients undergoing investigation of suspected Pneumocystis carinii …