User profiles for "author:T Osaki"

Tatsuya Osaki

Picower Institute for learning and memory Massachusetts Institute of Technology
Verified email at mit.edu
Cited by 2471

[HTML][HTML] Chitin, chitosan, and its derivatives for wound healing: old and new materials

K Azuma, R Izumi, T Osaki, S Ifuku, M Morimoto… - Journal of functional …, 2015 - mdpi.com
Chitin (β-(1-4)-poly-N-acetyl-d-glucosamine) is widely distributed in nature and is the
second most abundant polysaccharide after cellulose. It is often converted to its more …

[HTML][HTML] Superoxide radicals in the execution of cell death

J Fujii, T Homma, T Osaki - Antioxidants, 2022 - mdpi.com
Superoxide is a primary oxygen radical that is produced when an oxygen molecule receives
one electron. Superoxide dismutase (SOD) plays a primary role in the cellular defense …

[HTML][HTML] Anticancer and anti-inflammatory properties of chitin and chitosan oligosaccharides

K Azuma, T Osaki, S Minami, Y Okamoto - Journal of functional …, 2015 - mdpi.com
Previous reports indicate that N-acetyl-d-glucosamine oligomers (chitin oligosaccharide;
NACOS) and d-glucosamine oligomers (chitosan oligosaccharide; COS) have various …

Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression

Y Oka, A Tsuboi, T Taguchi, T Osaki… - Proceedings of the …, 2004 - National Acad Sciences
The Wilms' tumor gene WT1 is overexpressed in leukemias and various types of solid
tumors, and the WT1 protein was demonstrated to be an attractive target antigen for …

Suppression of carbon deposition in the CO2-reforming of CH4 by adding basic metal oxides to a Ni/Al2O3 catalyst

T Horiuchi, K Sakuma, T Fukui, Y Kubo, T Osaki… - Applied Catalysis A …, 1996 - Elsevier
The effect of the oxides of Na, K, Mg, and Ca on CO2-reforming of CH4 over Ni Al 2O 3
catalysts was studied from the viewpoint of carbon deposition. These added oxides …

Peripheral lung adenocarcinoma: correlation of thin-section CT findings with histologic prognostic factors and survival

…, H Nakata, T Kasai, H Hashimoto, M Kodate, T Osaki… - Radiology, 2001 - pubs.rsna.org
PURPOSE: To evaluate the prognostic importance of thin-section computed tomographic
(CT) findings of peripheral lung adenocarcinomas. MATERIALS AND METHODS: The …

Oxidative steam reforming of methanol over CuZnAl (Zr)-oxide catalysts for the selective production of hydrogen for fuel cells: catalyst characterization and …

S Velu, K Suzuki, M Okazaki, MP Kapoor, T Osaki… - Journal of catalysis, 2000 - Elsevier
A new series of CuZnAl (Zr)-oxide catalysts were prepared by the decomposition of CuZnAl
(Zr)-hydroxycarbonate precursors containing hydrotalcite (HT)-like layered double hydroxide …

[HTML][HTML] 3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes

M Campisi, Y Shin, T Osaki, C Hajal, V Chiono… - Biomaterials, 2018 - Elsevier
The blood-brain barrier (BBB) regulates molecular trafficking, protects against pathogens,
and prevents efficient drug delivery to the brain. Models to date failed to reproduce the …

[HTML][HTML] An immune-responsive Serpin regulates the melanization cascade in Drosophila

E De Gregorio, SJ Han, WJ Lee, MJ Baek, T Osaki… - Developmental cell, 2002 - cell.com
In arthropods, the melanization reaction is associated with multiple host defense
mechanisms leading to the sequestration and killing of invading microorganisms. Arthropod …

IFN-γ-inducing factor/IL-18 administration mediates IFN-γ-and IL-12-independent antitumor effects

T Osaki, JM Péron, Q Cai, H Okamura… - The Journal of …, 1998 - journals.aai.org
We evaluated the mechanism of the antitumor effects of mouse rIFN-γ-inducing factor/IL-18
protein on the growth of mouse tumor cell lines in vivo. Mice received IL-18 before or after …