Idiopathic pulmonary fibrosis is a progressive and usually fatal lung disease characterized
by fibroblast proliferation and extracellular matrix remodeling, which result in irreversible …

Idiopathic pulmonary fibrosis is a devastating, age-related lung disease of unknown cause
that has few treatment options. This disease was once thought to be a chronic inflammatory …

The natural history of idiopathic pulmonary fibrosis (IPF) has been characterized as a
steady, predictable decline in lung function over time. Recent evidence suggests that some …

This document is an international evidence-based guideline on the diagnosis and
management of idiopathic pulmonary fibrosis, and is a collaborative effort of the American …

Abstract Ever since Stephen Paget's 1889 hypothesis, metastatic organotropism has
remained one of cancer's greatest mysteries. Here we demonstrate that exosomes from …

Background: In 2002 the American Thoracic Society/European Respiratory Society
(ATS/ERS) classification of idiopathic interstitial pneumonias (IIPs) defined seven specific …

We analysed whole-genome sequences of 560 breast cancers to advance understanding of
the driver mutations conferring clonal advantage and the mutational processes generating …

Invasive lobular carcinoma (ILC) is the second most prevalent histologic subtype of invasive
breast cancer. Here, we comprehensively profiled 817 breast tumors, including 127 ILC, 490 …

Background In two of three phase 3 trials, pirfenidone, an oral antifibrotic therapy, reduced
disease progression, as measured by the decline in forced vital capacity (FVC) or vital …

MOSFETs with gate length down to 17 nm are reported. To suppress the short channel
effect, a novel self-aligned double-gate MOSFET, FinFET, is proposed. By using boron …