[HTML][HTML] Small extracellular vesicle targeting of hypothalamic AMPKα1 promotes weight loss in leptin receptor deficient mice

E Milbank, N Dragano, X Vidal-Gómez… - Metabolism, 2023 - Elsevier
Background and aims Leptin receptor (LEPR) deficiency promotes severe obesity and
metabolic disorders. However, the current therapeutic options against this syndrome are …

Effect of mandibular advancement therapy on inflammatory and metabolic biomarkers in patients with severe obstructive sleep apnoea: a randomised controlled trial

S Recoquillon, JL Pépin, B Vielle, R Andriantsitohaina… - Thorax, 2019 - thorax.bmj.com
Systemic inflammation and metabolic disorders are among the mechanisms linking
obstructive sleep apnoea (OSA) and cardiovascular disease (CVD). In 109 patients with …

Faeces‐derived extracellular vesicles participate in the onset of barrier dysfunction leading to liver diseases

L Fizanne, A Villard, N Benabbou… - Journal of …, 2023 - Wiley Online Library
The role of extracellular vesicles (EVs) from faeces (fEVs) and small circulating EVs (cEVs)
in liver diseases such as non‐alcoholic fatty diseases (NAFLD) and non‐alcoholic …

Nonmuscle myosin light chain kinase: a key player in intermittent hypoxia‐induced vascular alterations

C Arnaud, S Bouyon, S Recoquillon… - Journal of the …, 2018 - Am Heart Assoc
Background Obstructive sleep apnea is characterized by repetitive pharyngeal collapses
during sleep, leading to intermittent hypoxia (IH), the main contributor of obstructive sleep …

[HTML][HTML] Small Extracellular Vesicles Harboring PD-L1 in Obstructive Sleep Apnea

S Recoquillon, S Ali, G Justeau, J Riou… - International Journal of …, 2024 - mdpi.com
Obstructive sleep apnea syndrome (OSA) has been associated with increased cancer
incidence and aggressiveness. One hypothesis to support this association is the implication …

[HTML][HTML] Non-muscular myosin light chain kinase triggers intermittent hypoxia-induced interleukin-6 release, endothelial dysfunction and permeability

S Recoquillon, M Gómez-Guzmán, M Rodier, C Koffi… - Scientific reports, 2017 - nature.com
Obstructive sleep apnea is characterized by intermittent hypoxia (IH) which alters
endothelial function, induces inflammation and accelerates atherosclerosis-induced …

[HTML][HTML] Polyphenols have no impact on endothelial function in patients with obstructive sleep apnea: a randomized controlled trial

W Trzepizur, V Bironneau, S Recoquillon, P Priou… - The Journal of …, 2018 - Elsevier
Background Endothelial dysfunction, a pathophysiologic determinant of atherogenesis, has
been found to occur in obstructive sleep apnea syndrome (OSA) and is improved by …

Interaction in endothelium of non-muscular myosin light-chain kinase and the NF-κB pathway is critical to lipopolysaccharide-induced vascular hyporeactivity

S Recoquillon, N Carusio, AH Lagrue-Lakhal… - Clinical …, 2015 - portlandpress.com
During sepsis, endothelial barrier dysfunction contributes to cardiovascular failure, mainly
through the release of oxidative metabolites by penetrant leukocytes. We reported the non …

Phostine 3.1 a as a pharmacological compound with antiangiogenic properties against diseases with excess vascularization

S Bousseau, M Marchand, R Soleti… - The FASEB …, 2019 - Wiley Online Library
Angiogenesis is a complex process leading to the growth of new blood vessels from existing
vasculature, triggered by local proangiogenic factors such as VEGF. An excess of …

0319: Non muscular myosin light chain kinase (nmMLCK) and NF-κB pathway interaction in endothelium is critical for lipopolysaccharide-induced vascular …

S Recoquillon, N Carusio, AH Lagrue-Lakhal… - Archives of …, 2015 - Elsevier
The lipopolysaccharide (LPS) is a major component of the Gram-negative bacteria affects
cells of the vasculature causing hypotension by the initiation of smooth muscle cell …