[HTML][HTML] Tracking the evolution of non–small-cell lung cancer
M Jamal-Hanjani, GA Wilson… - … England Journal of …, 2017 - Mass Medical Soc
Background Among patients with non–small-cell lung cancer (NSCLC), data on intratumor
heterogeneity and cancer genome evolution have been limited to small retrospective …
heterogeneity and cancer genome evolution have been limited to small retrospective …
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
The early detection of relapse following primary surgery for non-small-cell lung cancer and
the characterization of emerging subclones, which seed metastatic sites, might offer new …
the characterization of emerging subclones, which seed metastatic sites, might offer new …
[PDF][PDF] Allele-specific HLA loss and immune escape in lung cancer evolution
Immune evasion is a hallmark of cancer. Losing the ability to present neoantigens through
human leukocyte antigen (HLA) loss may facilitate immune evasion. However, the …
human leukocyte antigen (HLA) loss may facilitate immune evasion. However, the …
[PDF][PDF] Fc effector function contributes to the activity of human anti-CTLA-4 antibodies
FA Vargas, AJS Furness, K Litchfield, K Joshi… - Cancer cell, 2018 - cell.com
With the use of a mouse model expressing human Fc-gamma receptors (FcγRs), we
demonstrated that antibodies with isotypes equivalent to ipilimumab and tremelimumab …
demonstrated that antibodies with isotypes equivalent to ipilimumab and tremelimumab …
[HTML][HTML] Evaluation of two short standardised regimens for the treatment of rifampicin-resistant tuberculosis (STREAM stage 2): an open-label, multicentre, randomised …
RL Goodall, SK Meredith, AJ Nunn, A Bayissa… - The Lancet, 2022 - thelancet.com
Background The STREAM stage 1 trial showed that a 9-month regimen for the treatment of
rifampicin-resistant tuberculosis was non-inferior to the 20-month 2011 WHO-recommended …
rifampicin-resistant tuberculosis was non-inferior to the 20-month 2011 WHO-recommended …
Bedaquiline, delamanid, linezolid, and clofazimine for treatment of pre-extensively drug-resistant tuberculosis
C Padmapriyadarsini, V Vohra… - Clinical Infectious …, 2023 - academic.oup.com
Background Treatment success rates for multidrug-resistant tuberculosis (MDR-TB) remain
low globally. Availability of newer drugs has given scope to develop regimens that can be …
low globally. Availability of newer drugs has given scope to develop regimens that can be …
Expansion of pathogen-specific T-helper 1 and T-helper 17 cells in pulmonary tuberculosis with coincident type 2 diabetes mellitus
NP Kumar, R Sridhar, VV Banurekha… - The Journal of …, 2013 - academic.oup.com
Background. Type 2 diabetes mellitus (DM) is a major risk factor for the development of
active pulmonary tuberculosis, although the immunological mechanisms underlying this …
active pulmonary tuberculosis, although the immunological mechanisms underlying this …
Type 2 diabetes mellitus coincident with pulmonary tuberculosis is associated with heightened systemic type 1, type 17, and other proinflammatory cytokines
NP Kumar, R Sridhar, VV Banurekha… - Annals of the …, 2013 - atsjournals.org
Rationale: Type 2 diabetes mellitus is a major risk factor for the development of active
tuberculosis, although the biological basis underlying this susceptibility remains poorly …
tuberculosis, although the biological basis underlying this susceptibility remains poorly …
[HTML][HTML] Systemic inflammation and the increased risk of inflamm-aging and age-associated diseases in people living with HIV on long term suppressive antiretroviral …
H Babu, AT Ambikan, EE Gabriel… - Frontiers in …, 2019 - frontiersin.org
The ART program in low-and middle-income countries (LMIC) like India, follows a public
health approach with a standardized regimen for all people living with HIV (PLHIV). Based …
health approach with a standardized regimen for all people living with HIV (PLHIV). Based …
[HTML][HTML] Impact of coronavirus 2019 (COVID-19) on training and well-being in subspecialty surgery: a national survey of cardiothoracic trainees in the United Kingdom
EJ Caruana, A Patel, S Kendall, S Rathinam - The Journal of Thoracic and …, 2020 - Elsevier
Abstract Objectives The coronavirus 2019 (COVID-19) pandemic has overwhelmed health
care systems and disrupted routine care internationally. Health care workers face disruption …
care systems and disrupted routine care internationally. Health care workers face disruption …