Effect of BCG vaccination against Mycobacterium tuberculosis infection in children: systematic review and meta-analysis

A Roy, M Eisenhut, RJ Harris, LC Rodrigues, S Sridhar… - Bmj, 2014 - bmj.com
Objectives To determine whether BCG vaccination protects against Mycobacterium
tuberculosis infection as assessed by interferon γ release assays (IGRA) in children. Design …

[HTML][HTML] Influenza vaccination strategies: comparing inactivated and live attenuated influenza vaccines

S Sridhar, KA Brokstad, RJ Cox - Vaccines, 2015 - mdpi.com
Influenza is a major respiratory pathogen causing annual outbreaks and occasional
pandemics. Influenza vaccination is the major method of prophylaxis. Currently annual …

[HTML][HTML] Heterosubtypic T-cell immunity to influenza in humans: challenges for universal T-cell influenza vaccines

S Sridhar - Frontiers in immunology, 2016 - frontiersin.org
Influenza A virus (IAV) remains a significant global health issue causing annual epidemics,
pandemics, and sporadic human infections with highly pathogenic avian or swine influenza …

[HTML][HTML] Cellular immune correlates of protection against symptomatic pandemic influenza

S Sridhar, S Begom, A Bermingham, K Hoschler… - Nature medicine, 2013 - nature.com
The role of T cells in mediating heterosubtypic protection against natural influenza illness in
humans is uncertain. The 2009 H1N1 pandemic (pH1N1) provided a unique natural …

[HTML][HTML] Effect of dengue serostatus on dengue vaccine safety and efficacy

S Sridhar, A Luedtke, E Langevin, M Zhu… - … England Journal of …, 2018 - Mass Medical Soc
Background In efficacy trials of a tetravalent dengue vaccine (CYD-TDV), excess
hospitalizations for dengue were observed among vaccine recipients 2 to 5 years of age …

[HTML][HTML] Prognostic value of interferon-γ release assays and tuberculin skin test in predicting the development of active tuberculosis (UK PREDICT TB): a prospective …

I Abubakar, F Drobniewski, J Southern… - The Lancet Infectious …, 2018 - thelancet.com
Background Tackling tuberculosis requires testing and treatment of latent tuberculosis in
high-risk groups. The aim of this study was to estimate the predictive values of the tuberculin …

Safety and immunogenicity of an AS03-adjuvanted SARS-CoV-2 recombinant protein vaccine (CoV2 preS dTM) in healthy adults: interim findings from a phase 2 …

S Sridhar, A Joaquin, MI Bonaparte… - The Lancet Infectious …, 2022 - thelancet.com
Background We evaluated our SARS-CoV-2 prefusion spike recombinant protein vaccine
(CoV2 preS dTM) with different adjuvants, unadjuvanted, and in a one-injection and two …

[HTML][HTML] Safety and immunogenicity of a variant-adapted SARS-CoV-2 recombinant protein vaccine with AS03 adjuvant as a booster in adults primed with authorized …

G de Bruyn, J Wang, A Purvis, MS Ruiz… - …, 2023 - thelancet.com
Background In a parallel-group, international, phase 3 study (ClinicalTrials. gov
NCT04762680), we evaluated prototype (D614) and Beta (B. 1.351) variant recombinant …

Clinical development of Ebola vaccines

S Sridhar - Therapeutic advances in vaccines, 2015 - journals.sagepub.com
The ongoing outbreak of Ebola virus disease in West Africa highlighted the lack of a
licensed drug or vaccine to combat the disease and has renewed the urgency to develop a …

Single‐dose immunogenicity and protective efficacy of simian adenoviral vectors against Plasmodium berghei

A Reyes‐Sandoval, S Sridhar… - European journal of …, 2008 - Wiley Online Library
Simian adenoviral vectors (SAd) offer an attractive alternative to standard human adenovirus
serotype 5 (AdH5) subunit vaccination, due to pre‐existing immunity affecting vaccine …