Review of acellular assays of ambient particulate matter oxidative potential: methods and relationships with composition, sources, and health effects
Oxidative stress is a potential mechanism of action for particulate matter (PM) toxicity and
can occur when the body's antioxidant capacity cannot counteract or detoxify harmful effects …
can occur when the body's antioxidant capacity cannot counteract or detoxify harmful effects …
Short-term associations between ambient air pollutants and pediatric asthma emergency department visits
MJ Strickland, LA Darrow, M Klein… - American journal of …, 2010 - atsjournals.org
Rationale: Certain outdoor air pollutants cause asthma exacerbations in children. To
advance understanding of these relationships, further characterization of the dose–response …
advance understanding of these relationships, further characterization of the dose–response …
Fine particle sources and cardiorespiratory morbidity: an application of chemical mass balance and factor analytical source-apportionment methods
JA Sarnat, A Marmur, M Klein, E Kim… - Environmental …, 2008 - ehp.niehs.nih.gov
Background Interest in the health effects of particulate matter (PM) has focused on
identifying sources of PM, including biomass burning, power plants, and gasoline and diesel …
identifying sources of PM, including biomass burning, power plants, and gasoline and diesel …
Reactive oxygen species generation linked to sources of atmospheric particulate matter and cardiorespiratory effects
Exposure to atmospheric fine particulate matter (PM2. 5) is associated with cardiorespiratory
morbidity and mortality, but the mechanisms are not well understood. We assess the …
morbidity and mortality, but the mechanisms are not well understood. We assess the …
Oxidative potential of ambient water-soluble PM in the southeastern United States: contrasts in sources and health associations between ascorbic acid (AA) and …
The ability of certain components of particulate matter to induce oxidative stress through the
generation of reactive oxygen species (ROS) in vivo may be one mechanism accounting for …
generation of reactive oxygen species (ROS) in vivo may be one mechanism accounting for …
Ambient pollen concentrations and emergency department visits for asthma and wheeze
BACKGROUND: Previous studies report associations between aeroallergen exposure and
asthma exacerbations. Aeroallergen burdens and asthma prevalence are increasing …
asthma exacerbations. Aeroallergen burdens and asthma prevalence are increasing …
Multipollutant modeling issues in a study of ambient air quality and emergency department visits in Atlanta
PE Tolbert, M Klein, JL Peel, SE Sarnat… - Journal of exposure …, 2007 - nature.com
Multipollutant models are frequently used to differentiate roles of multiple pollutants in
epidemiologic studies of ambient air pollution. In the presence of differing levels of …
epidemiologic studies of ambient air pollution. In the presence of differing levels of …
An examination of exposure measurement error from air pollutant spatial variability in time-series studies
SE Sarnat, M Klein, JA Sarnat, WD Flanders… - Journal of exposure …, 2010 - nature.com
Relatively few studies have evaluated the effects of heterogeneous spatiotemporal pollutant
distributions on health risk estimates in time-series analyses that use data from a central …
distributions on health risk estimates in time-series analyses that use data from a central …
Associations between source-specific fine particulate matter and emergency department visits for respiratory disease in four US cities
Background: Short-term exposure to ambient fine particulate matter (PM2. 5) concentrations
has been associated with increased mortality and morbidity. Determining which sources of …
has been associated with increased mortality and morbidity. Determining which sources of …
Use of high-resolution metabolomics for the identification of metabolic signals associated with traffic-related air pollution
Background High-resolution metabolomics (HRM) is emerging as a sensitive tool for
measuring environmental exposures and biological responses. The aim of this analysis is to …
measuring environmental exposures and biological responses. The aim of this analysis is to …