Importance Cannabis and cannabinoid drugs are widely used to treat disease or alleviate
symptoms, but their efficacy for specific indications is not clear. Objective To conduct a …

Understanding the factors that determine the rate at which genomes generate and fix
mutations provides important insights into key evolutionary mechanisms. We review our …

The results of the Swedish two-county trial of mammographic screening for breast cancer
are presented, updated to December 31, 1990, which is an average of 10.8 years' follow-up …

Background Somatic mutations have the potential to encode “non-self” immunogenic
antigens. We hypothesized that tumors with a large number of somatic mutations due to …

Background Colorectal cancer is the third most common cancer worldwide and has a high
mortality rate. We tested the hypothesis that only one flexible sigmoidoscopy screening …

The aims of this chapter are to:• Illustrate in practical terms the decision making processes
involved in the application of the guidance to a specific narrative synthesis• Identify factors …

Background The COVID-19 pandemic has placed unprecedented strain on health-care
systems. Frailty is being used in clinical decision making for patients with COVID-19, yet the …

Two experiments investigated whether lexical complexity increases a word's processing
time. Subjects read sentences, each containing a target word, while their eye movements …

Purpose To estimate the long-term (29-year) effect of mammographic screening on breast
cancer mortality in terms of both relative and absolute effects. Materials and Methods This …

In two studies, a newly devised test (framed-line test) was used to examine the hypothesis
that individuals engaging in Asian cultures are more capable of incorporating contextual …