Purpose Recent research has shown that chronic dietary beta-alanine (betaALA)
supplementation increases muscle carnosine content, which is associated with better …

Exercise tolerance is impaired in hypoxia, and it has recently been shown that dietary nitrate
supplementation can reduce the oxygen (O2) cost of muscle contractions. Therefore, we …

In humans, nutrient deprivation and extreme endurance exercise both activate autophagy.
We hypothesized that cumulating fasting and cycling exercise would potentiate activation of …

Key points Overload training is required for sustained performance gain in athletes
(functional overreaching). However, excess overload may result in a catabolic state which …

Purpose: Ketone bodies are energy substrates produced by the liver during prolonged
fasting or low-carbohydrate diet. The ingestion of a ketone ester (KE) rapidly increases …

Introduction Ageing is associated with an attenuated hypertrophic response to resistance
training and periods of training interruptions. Hence, elderly would benefit from the 'muscle …

Aims Eighteen patients with asthma were evaluated during preparation to climb to extreme
altitude in order to study the effects of low fractional inspired oxygen (FiO2), prolonged …

Aim To determine whether repeated maximal‐intensity hypoxic exercise induces larger
beneficial adaptations on the hypoxia‐inducible factor‐1α pathway and its target genes than …

Needle biopsies are being extensively used in clinical trials addressing muscular adaptation
to exercise and diet. Still, the potential artifacts due to biopsy sampling are often overlooked …

De novo capillarization is a primary muscular adaptation to endurance exercise training and
is crucial to improving performance. Excess training load, however, impedes such beneficial …