Objective To examine risk of malignancy and death in patients with kidney transplant who
receive the immunosuppressive drug sirolimus. Design Systematic review and meta …

Background: The long-term risk for major bleeding in patients receiving extended (beyond
the initial 3 to 6 months) anticoagulant therapy for a first unprovoked venous …

2. Methods We prospectively registered our systematic review with the International
Prospective Register of Systematic Reviews (PROSPERO)(CRD42012002078). We then …

Background Patients with active cancer have an increased risk of venous thromboembolism,
which results in substantial morbidity, mortality, and health care expenditures. The Khorana …

Importance Although asthma is a chronic disease, the expected rate of spontaneous
remissions of adult asthma and the stability of diagnosis are unknown. Objective To …

Objective: Delirium is common during critical illness and associated with adverse outcomes.
We compared characteristics and outcomes of delirious and nondelirious patients enrolled …

Background Placenta-mediated pregnancy complications include pre-eclampsia, late
pregnancy loss, placental abruption, and birth of a small-for-gestational-age (SGA) neonate …

Phthalates and bisphenol A (BPA) are high production volume and ubiquitous chemicals
that are quickly metabolized in the body. Traditionally, studies have relied on single spot …

Parabens are broad-spectrum antimicrobial preservatives and fragrances used in a wide
range of personal care products, pharmaceuticals, and food providing the opportunity for …

Purpose The purpose was to describe characteristics and outcomes of restrained and
nonrestrained patients enrolled in a randomized trial of protocolized sedation compared with …