Purpose Since treatment efficacy of cisplatin-or carboplatin-based chemotherapy in the first-
line treatment of small-cell lung cancer (SCLC) remains contentious, a meta-analysis of …

This chapter describes the components of the initial evaluation for a patient either suspected
or known to have lung cancer. The components of the initial evaluation are based on the …

Objectives: The non-small cell lung cancer (NSCLC) meta-analysis suggested a survival
benefit for cisplatin-based chemotherapy when given in addition to surgery, radical …

PURPOSE: Chemotherapy for non–small-cell lung cancer (NSCLC) remains controversial.
We describe the two largest reported, randomized, parallel trials designed to determine …

Prognostic factors can help clinicians and patients when deciding a treatment plan. Patients
in the best prognostic groups can be considered for more intensive or experimental therapy …

The preoperative physiologic assessment of a patient being considered for surgical
resection of lung cancer must consider the immediate perioperative risks from comorbid …

PURPOSE:: Gemcitabine–platinum combination activity has been clearly established in a
number of phase II studies. It has also been compared against other combinations in many …

Background: In 1995 a meta-analysis of randomised trials investigating the value of adding
chemotherapy to primary treatment for non-small cell lung cancer (NSCLC) suggested a …

A minority of patients with cryptogenic fibrosing alveolitis (idiopathic pulmonary fibrosis)
respond to treatment with corticosteroids. The purpose of this study was to identify factors …

Purpose: Malignant pleural mesothelioma (MPM) is an increasing health burden on many
societies worldwide and, being generally resistant to conventional treatment, has a poor …