The natural ends of linear chromosomes require unique genetic and structural adaptations
to facilitate the protection of genetic material. This is achieved by the sequestration of the …

Histone N-termini (tails) undergo diverse post-translational modifications, including
acetylation, phosphorylation, methylation, ubiquitination and ADP-ribosylation (van Holde …

Background Globally, populations are ageing. Typically, physical activity levels decline and
health worsens as we age; however, estimates of the impact of physical inactivity for …

Methylation of position-specific lysine residues in histone N termini is a central modification
for regulating epigenetic transitions in chromatin. Each methylatable lysine residue can exist …

Histone lysine methylation has important roles in the organization of chromatin domains and
the regulation of gene expression. To analyze its function and modulate its activity, we …

Background: The new technique of functional magnetic resonance imaging was used to
investigate the mediating neuroanatomy of obsessive-compulsive disorder symptoms …

Neuroblastoma is a malignant paediatric tumour of the sympathetic nervous system.
Roughly half of these tumours regress spontaneously or are cured by limited therapy. By …

Histone lysine methylation has been shown to index silenced chromatin regions at, for
example, pericentric heterochromatin or of the inactive X chromosome. Here, we examined …

PURPOSE: To determine the histopathologic findings of patellar tendinosis (" jumper's
knee") demonstrated with ultrasonography (US) and magnetic resonance (MR) imaging …

Transverse, low‐frequency oscillations in the magnetic field have been recorded in the
equatorial plane at 6.6 RE (earth radii) with the UCLA magnetometer on board ATS 1. The …