The 12-minute walking test'is a useful and reproducible1 2 measure of exercise tolerance. It
provides a simple, practical guide to everyday disability and does not require expensive …

Discussion Cutaneous larva migrans is usually caused by the larvae of the nematode
Ancylostoma braziliense, the dog or cat hookworm. Dogs and cats contaminate the ground …

Ventilation, heart rate, and arterial blood gas tensions were measured at rest and during
incremental exercise in 10 patients with emphysema after intravenous placebo or 7 mg …

1 Minute ventilation, alveolar PCO2, CO2 production and heart rate were measured in eight
normal subjects before and during infusions of noradrenaline 0.2, 1.0 and 5.0 micrograms …

First-pass lung uptake of propranolol in catheterized ambulant dogs was measured by
comparison the difference between the ratios of [14C] propranolol to indocyanine green …

Ten patients with severe dyspnoea and chronic airflow obstruction entered a randomised
double-blind crossover trial comparing the effect of carbimazole 80 mg daily for two months …

A patient with a primary cardiac angiosarcoma developed two previously unreported
manifestations: cardiac rupture, which has not been reported with any primary cardiac …

We present combined photometric and spectroscopic analyses of the multiple star V454
Carinae. High-resolution spectra of the system were taken at the University of Canterbury Mt …

SIR,-Professor Geoffrey Rose in his letter (19 April, p 1099) rightly drew attention to the need
to give confidence limits in" negative" trials such as that recently reported with betablockers …

We report a patient with fibrosing alveolitis associated with amiodarone therapy. Review of
the literature suggests that amiodarone induced pulmonary disease generally occurs on a …