Lung clearance index is a sensitive, repeatable and practical measure of airways disease in adults with cystic fibrosis

AR Horsley, PM Gustafsson, KA Macleod, C Saunders… - Thorax, 2008 - thorax.bmj.com
Background: Lung clearance index (LCI) is a sensitive marker of early lung disease in
children but has not been assessed in adults. Measurement is hindered by the complexity of …

Body mass index status and peripheral airway obstruction in school-age children: a population-based cohort study

S Ekström, J Hallberg, I Kull, JLP Protudjer, P Thunqvist… - Thorax, 2018 - thorax.bmj.com
Background Few large prospective studies have investigated the impact of body mass index
(BMI) on lung function during childhood. Methods Using data collected between 2002 and …

Novel methodology to perform sulfur hexafluoride (SF6)-based multiple-breath wash-in and washout in infants using current commercially available equipment

PM Gustafsson, PD Robinson… - Journal of Applied …, 2016 - journals.physiology.org
Multiple-breath inert gas washout (MBW) is ideally suited for early detection and monitoring
of serious lung disease, such as cystic fibrosis, in infants and young children. Validated …

Ventilation inhomogeneity in infants with recurrent wheezing

Z Lu, RE Foong, K Kowalik, TJ Moraes, A Boyce… - Thorax, 2018 - thorax.bmj.com
Background The care of infants with recurrent wheezing relies largely on clinical
assessment. The lung clearance index (LCI), a measure of ventilation inhomogeneity, is a …

Longitudinal lung clearance index and association with structural lung damage in children with cystic fibrosis

M Svedberg, H Imberg, PM Gustafsson, H Tiddens… - Thorax, 2023 - thorax.bmj.com
Children with cystic fibrosis (CF) now often go through childhood with only subtle upper and
lower airway-related symptoms and have well-preserved lung function assessed by …