Objective To determine the validity of the esophageal Doppler monitor (EDM) and echo-
esophageal Doppler (Echo-ED) in measuring cardiac output in the critically ill. Design …

Early infection diagnosis as the cause of a patient's systemic inflammatory syndrome is an
important facet of sepsis care bundles aimed at saving lives. Microbiological culture …

Objective: To analyze the evacuation preparedness of hospitals within the European Union
(EU). Method: This study consisted of 2 steps. In the first step, a systematic review of the …

Background Participants in clinical research studies often do not reflect the populations for
which healthcare interventions are needed or will be used. Enhancing representation of …

Background Continuous positive airways pressure (CPAP) and high-flow nasal oxygen
(HFNO) are considered 'aerosol-generating procedures' in the treatment of COVID-19 …

Molecular oxygen has been previously shown to shorten longitudinal relaxation time (T1) in
the spleen and renal cortex, but not in the liver or fat. In this study, the magnitude and …

Background Healthcare associated infections, including ventilator associated pneumonia,
are difficult to diagnose and treat, and are associated with significant morbidity, mortality and …

Objective To provide guidance to researchers, funders, regulators and study delivery teams
to ensure that research on COVID-19 is inclusive, particularly of groups disproportionately …

Invasive arterial pressure monitoring is one of the most frequent monitoring techniques used
in critically ill patients and in anaesthetized subjects in whom rapid changes in the …

Background COVID-19 has become the most common cause of acute respiratory distress
syndrome (ARDS) worldwide. Features of the pathophysiology and clinical presentation …