The prevalence and incidence of systemic sclerosis (SSc) in The Netherlands is unknown.
The same holds true for its leading causes of death: pulmonary fibrosis and pulmonary …

Rationale: In cystic fibrosis (CF), lung disease is the predominant cause of morbidity and
mortality. Little is known about the spectrum of structural abnormalities on CT scans from …

Abstract Treatment of cytomegalovirus (CMV) disease in transplant patients is challenging
and, with antiviral resistance to first‐line drugs, it remains uncertain which treatment …

A patient with therapy‐resistant and progressive systemic sclerosis (SSc) with pulmonary
involvement who was treated with imatinib mesylate is described herein. Prior to treatment …

Summary Background and Objectives Preliminary studies indicated that α 1‐antitrypsin
(A1AT) is the most abundant protein that is non‐covalently bound to fibrin clots prepared …

To evaluate indicators of inflammatory changes in the airways of young smokers we have
measured the levels of several eicosanoids in bronchoalveolar lavage (BAL) fluid of 18 …

A continuous influx of peripheral blood monocytes (PBM) to the lung is thought to maintain
the local population of alveolar macrophages (AM). However, local proliferation of a small …

Previously, we found that inflammatory mediators modulated the number and binding affinity
of glucocorticoid receptors (GR) in human bronchial epithelial cell lines. In this study we …

Among patients with asthma or chronic obstructive pulmonary diseases the response to
glucocorticoids varies considerably. To investigate the possible relationship between clinical …

The CD11/CD18 leukocyte surface adhesion glycoprotein family consists of three different
heterodimeric molecules which play an essential role in adhesion-related functions such as …