Hypersecretion of airway mucus is a characteristic feature of chronic airway diseases like
cystic fibrosis (CF) and leads via impairment of the muco-ciliary clearance and bacterial …

Expression of respiratory mucins in fatal status asthmaticus and mild asthma Aims: The
airways of patients with asthma are characterized by chronic inflammatory changes …

The nature of protein breakdown products and peptidomimetic drugs such as β-lactams is
crucial for their transmembrane transport across apical enterocyte membranes, which is …

Abstract Objectives/Hypothesis The upper respiratory tract is involved in many acute and
chronic respiratory tract diseases that present with the symptom of mucus hypersecretion …

Background: Aerosol administration of peptide based drugs has an important role in the
treatment of various pulmonary and systemic diseases. The characterisation of pulmonary …

Chronic cellular inflammation and airway wall remodelling with subepithelial fibrosis and
airway smooth muscle (ASM) cell hyperplasia are features of chronic asthma. Jun N …

Chronic cellular inflammation and airway wall remodeling with subepithelial fibrosis and
airway smooth muscle thickening are features of chronic asthma. We determined the role of …

The role of nitric oxide (NO) in allergic inflammation and bronchial hyperresponsiveness is
unclear. We studied a selective prodrug nitric oxide synthase (NOS)-2 inhibitor, l-N6-(1 …

Repeated ovalbumin (OA) or saline exposure of sensitized Brown Norway rats was
examined on agonist reactivity, airway smooth muscle (ASM) content, and contractile protein …

Jun N‐terminal kinase (JNK) has been implicated in the pathogenesis of inflammatory
diseases including asthma. We examined the effect of SP600125 (anthra [1, 9‐cd] pyrazol‐6 …