An official American Thoracic Society/European Respiratory Society statement: research questions in chronic obstructive pulmonary disease

BR Celli, M Decramer, JA Wedzicha… - American journal of …, 2015 - atsjournals.org
Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of
morbidity, mortality, and resource use worldwide. The goal of this Official American Thoracic …

An official American Thoracic Society statement: update on the mechanisms, assessment, and management of dyspnea

MB Parshall, RM Schwartzstein, L Adams… - American journal of …, 2012 - atsjournals.org
Background: Dyspnea is a common, distressing symptom of cardiopulmonary and
neuromuscular diseases. Since the ATS published a consensus statement on dyspnea in …

Roflumilast: a review of its use in the treatment of COPD

JA Wedzicha, PM Calverley… - International journal of …, 2016 - Taylor & Francis
COPD is a progressive condition involving chronic inflammation and parenchymal
destruction with resulting airflow limitation. COPD is associated with worsening airflow …

Chronic obstructive pulmonary disease phenotypes: the future of COPD

MLK Han, A Agusti, PM Calverley, BR Celli… - American journal of …, 2010 - atsjournals.org
Significant heterogeneity of clinical presentation and disease progression exists within
chronic obstructive pulmonary disease (COPD). Although FEV1 inadequately describes this …

Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)

J Bousquet, J Farrell, G Crooks… - Clinical and …, 2016 - Wiley Online Library
Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP
on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was …

Maintenance therapy with budesonide and formoterol in chronicobstructive pulmonary disease

PM Calverley, W Boonsawat, Z Cseke… - European …, 2003 - Eur Respiratory Soc
Lung function in chronic obstructive pulmonary disease (COPD) can be improved acutely by
oral corticosteroids and bronchodilators. Whether clinical improvement can be maintained …

Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials

M Bafadhel, S Peterson, MA De Blas… - The Lancet …, 2018 - thelancet.com
Background The peripheral blood eosinophil count might help identify those patients with
chronic obstructive pulmonary disease (COPD) who will experience fewer exacerbations …

Inhaled corticosteroids and mortality in chronic obstructive pulmonary disease

DD Sin, L Wu, JA Anderson, NR Anthonisen, AS Buist… - Thorax, 2005 - thorax.bmj.com
Background: Clinical studies suggest that inhaled corticosteroids reduce exacerbations and
improve health status in chronic obstructive pulmonary disease (COPD). However, their …

Bronchodilator reversibility, exercise performance and breathlessness in stable chronic obstructive pulmonary disease

JG Hay, P Stone, J Carter, S Church… - European …, 1992 - Eur Respiratory Soc
Partial bronchodilator reversibility can be demonstrated in many patients with stable chronic
obstructive pulmonary disease (COPD), but its relevance to exercise capacity and symptoms …

Simultaneous tracheal and oesophageal pH measurements in asthmatic patients with gastro-oesophageal reflux.

CI Jack, PM Calverley, RJ Donnelly, J Tran, G Russell… - Thorax, 1995 - thorax.bmj.com
BACKGROUND--An association between asthma and gastro-oesophageal reflux is well
recognised but the underlying mechanism is unclear. One suggestion is that gastric juice is …