Acute exacerbations of chronic obstructive pulmonary disease are accompanied by elevations of plasma fibrinogen and serum IL-6 levels

JA Wedzicha, TAR Seemungal… - Thrombosis and …, 2000 - thieme-connect.com
Respiratory tract infections may acutely increase risk from coronary heart disease (CHD),
though the mechanisms have not been defined. Patients with chronic obstructive pulmonary …

[HTML][HTML] The incidence and magnitude of fibrinolytic activation in trauma patients

I Raza, R Davenport, C Rourke, S Platton… - Journal of Thrombosis …, 2013 - Elsevier
Background: Trauma is a global disease, with over 2.5 million deaths annually from
hemorrhage and coagulopathy. Overt hyperfibrinolysis is rare in trauma, and is associated …

Airway and systemic inflammation and decline in lung function in patients with COPD

GC Donaldson, TAR Seemungal, IS Patel, A Bhowmik… - Chest, 2005 - Elsevier
Study objectives Patients with COPD experience lower airway and systemic inflammation,
and an accelerated decline in FEV 1. There is no evidence on whether this inflammation …

Markers of hemostasis and systemic inflammation in heart disease and atherosclerosis in smokers

PK MacCallum - Proceedings of the American Thoracic Society, 2005 - atsjournals.org
Smoking is a major cause of both chronic obstructive pulmonary disease (COPD) and
coronary heart disease, the latter being more common in individuals with COPD. Acute …

Multicentre randomised study of computerised anticoagulant dosage

L Poller, CR Shiach, PK MacCallum, AM Johansen… - The Lancet, 1998 - thelancet.com
Background The demand for anticoagulant treatment is increasing. We compared the
benefits of computer-generated anticoagulant dosing with traditional dosing decided by …

Platelet activation and endogenous thrombin potential in pre-eclampsia

MG Macey, S Bevan, S Alam, L Verghese, S Agrawal… - Thrombosis research, 2010 - Elsevier
INTRODUCTION: Platelets and the coagulation system may be involved in the pathogenesis
of pre-eclampsia. We investigated whether platelet and coagulation activation markers, are …

Patient safety and estimation of renal function in patients prescribed new oral anticoagulants for stroke prevention in atrial fibrillation: a cross-sectional study

PK MacCallum, R Mathur, SA Hull, K Saja, L Green… - BMJ open, 2013 - bmjopen.bmj.com
Objective In clinical trials of dabigatran and rivaroxaban for stroke prevention in atrial
fibrillation (AF), drug eligibility and dosing were determined using the Cockcroft-Gault …

Associations of haemostatic variables with body mass index: a community-based study

LK Bowles, JA Cooper, DJ Howarth… - Blood coagulation & …, 2003 - journals.lww.com
Obesity is a risk factor for venous and arterial thrombosis. We examined relationships
between body mass index (BMI) and a number of haemostatic and inflammatory variables in …

Chlamydia pneumoniae and COPD exacerbation

TAR Seemungal, JA Wedzicha, PK MacCallum… - Thorax, 2002 - thorax.bmj.com
We are writing to express our unease at what we believe is inappropriate censure imposed
on our colleague Professor Corris concerning duplicate publications. 1 2 Professor Corris …

Impairment of coagulation by commonly used resuscitation fluids in human volunteers

TJ Coats, E Brazil, M Heron… - Emergency medicine …, 2006 - emj.bmj.com
Background: This study compared the effects of two commonly used resuscitation fluids on
whole blood coagulation. Methods: 1000 ml of two resuscitation fluids each (saline and …