The hypothesis that the small conducting airways were the major site of obstruction to airflow
in normal lungs was introduced by Rohrer in 1915 and prevailed until Weibel introduced a …

Airway wall remodeling is well documented for asthmatic airways and is believed to result
from chronic and/or short-term exposure to inflammatory stimuli. Airway wall remodeling can …

Smoking-related lung diseases such as chronic obstructive pulmonary disease (COPD) and
lung cancer are growing epidemics in women in the United States and elsewhere. Although …

Background Chronic obstructive pulmonary disease (COPD) is a major public health
problem associated with long-term exposure to toxic gases and particles. We examined the …

Background The major sites of obstruction in chronic obstructive pulmonary disease (COPD)
are small airways (< 2 mm in diameter). We wanted to determine whether there was a …

Objective Dysbiosis of the infant gut microbiota may have long‐term health consequences.
This study aimed to determine the impact of maternal intrapartum antibiotic prophylaxis (IAP) …

This study was designed to determine the potential importance of airway wall thickening in
the pathogenesis of the excess airways narrowing of asthma. The airways in postmortem …

Chronic obstructive pulmonary disease (COPD) is characterized by the presence of airflow
obstruction caused by emphysema or airway narrowing, or both. Low attenuation areas …

Background Understanding the genetic basis of airflow obstruction and smoking behaviour
is key to determining the pathophysiology of chronic obstructive pulmonary disease (COPD) …

The purpose of this study was to compare the dimensions of the peripheral airways in fatal
asthma with those from patients with nonfatal asthma, mild COPD, and normal lung function …