Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape

NI Mazur, J Terstappen, R Baral, A Bardají… - The Lancet Infectious …, 2023 - thelancet.com
Respiratory syncytial virus is the second most common cause of infant mortality and a major
cause of morbidity and mortality in older adults (aged> 60 years). Efforts to develop a …

The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates

NI Mazur, D Higgins, MC Nunes, JA Melero… - The Lancet Infectious …, 2018 - thelancet.com
The global burden of disease caused by respiratory syncytial virus (RSV) is increasingly
recognised, not only in infants, but also in older adults (aged≥ 65 years). Advances in …

Respiratory syncytial virus seasonality: a global overview

P Obando-Pacheco, AJ Justicia-Grande… - The Journal of …, 2018 - academic.oup.com
Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory infections in
children. By the age of 1 year, 60%–70% of children have been infected by RSV. In addition …

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

MPR Berry, CM Graham, FW McNab, Z Xu, SAA Bloch… - Nature, 2010 - nature.com
Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis, is a major cause of
morbidity and mortality worldwide. Efforts to control it are hampered by difficulties with …

[PDF][PDF] A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus

D Chaussabel, C Quinn, J Shen, P Patel, C Glaser… - Immunity, 2008 - cell.com
The analysis of patient blood transcriptional profiles offers a means to investigate the
immunological mechanisms relevant to human diseases on a genome-wide scale. In …

Induction of ICOS+CXCR3+CXCR5+ TH Cells Correlates with Antibody Responses to Influenza Vaccination

SE Bentebibel, S Lopez, G Obermoser… - Science translational …, 2013 - science.org
Seasonal influenza vaccine protects 60 to 90% of healthy young adults from influenza
infection. The immunological events that lead to the induction of protective antibody …

Gene expression patterns in blood leukocytes discriminate patients with acute infections

O Ramilo, W Allman, W Chung, A Mejias, M Ardura… - Blood, 2007 - ashpublications.org
Each infectious agent represents a unique combination of pathogen-associated molecular
patterns that interact with specific pattern-recognition receptors expressed on immune cells …

[HTML][HTML] Challenges in infant immunity: implications for responses to infection and vaccines

M PrabhuDas, B Adkins, H Gans, C King, O Levy… - Nature …, 2011 - nature.com
Challenges in infant immunity: implications for responses to infection and vaccines | Nature
Immunology Skip to main content Thank you for visiting nature.com. You are using a browser …

Mapping systemic lupus erythematosus heterogeneity at the single-cell level

D Nehar-Belaid, S Hong, R Marches, G Chen… - Nature …, 2020 - nature.com
Patients with systemic lupus erythematosus (SLE) display a complex blood transcriptome
whose cellular origin is poorly resolved. Using single-cell RNA sequencing, we profiled …

Nasopharyngeal microbiota, host transcriptome, and disease severity in children with respiratory syncytial virus infection

WAA de Steenhuijsen Piters, S Heinonen… - American journal of …, 2016 - atsjournals.org
Rationale: Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory
tract infections and hospitalizations in infants worldwide. Known risk factors, however …