Tidal changes on CT and progression of ARDS
Background Uncertain prediction of outcome in acute respiratory distress syndrome (ARDS)
impedes individual patient management and clinical trial design. Objectives To develop a …
impedes individual patient management and clinical trial design. Objectives To develop a …
Unstable inflation causing injury. Insight from prone position and paired computed tomography scans
Rationale: It remains unclear how prone positioning improves survival in acute respiratory
distress syndrome. Using serial computed tomography (CT), we previously reported that …
distress syndrome. Using serial computed tomography (CT), we previously reported that …
Visualizing the propagation of acute lung injury
Background Mechanical ventilation worsens acute respiratory distress syndrome, but this
secondary “ventilator-associated” injury is variable and difficult to predict. The authors aimed …
secondary “ventilator-associated” injury is variable and difficult to predict. The authors aimed …
Semiautomatic segmentation of longitudinal computed tomography images in a rat model of lung injury by surfactant depletion
Quantitative analysis of computed tomography (CT) is essential to the study of acute lung
injury. However, quantitative CT is made difficult by poor lung aeration, which complicates …
injury. However, quantitative CT is made difficult by poor lung aeration, which complicates …
Mild loss of lung aeration augments stretch in healthy lung regions
Inspiratory stretch by mechanical ventilation worsens lung injury. However, it is not clear
whether and how the ventilator damages lungs in the absence of preexisting injury. We …
whether and how the ventilator damages lungs in the absence of preexisting injury. We …
[HTML][HTML] Severe psychiatric symptoms in a patient with EGFR exon-20 insertion mutation receiving mobocertinib: a case report
J Kamel, N Meeder, S Cuellar, D Chan, M Huber… - JTO Clinical and …, 2021 - Elsevier
Tyrosine kinase inhibitor therapy is an established standard of care for patients with NSCLC
with EGFR mutations, but a worse prognosis has been observed in patients with specific …
with EGFR mutations, but a worse prognosis has been observed in patients with specific …
Hyperpolarized gas diffusion MRI of biphasic lung inflation in short-and long-term emphysema models
During lung inflation, airspace dimensions are affected nonlinearly by both alveolar
expansion and recruitment, potentially confounding the identification of emphysematous …
expansion and recruitment, potentially confounding the identification of emphysematous …
Parametric response maps to measure the effects of prone position in pigs with experimental lung injury
Rationale: during mechanical ventilation and predict the effects of ventilator induced injury in
rats (Am J Respir Crit Care Med 2016; A6621). In this experiment, we aimed to study the …
rats (Am J Respir Crit Care Med 2016; A6621). In this experiment, we aimed to study the …
Clinical outcomes in patients with metastatic non-small cell lung cancer and head and neck squamous cell cancer treated with immune checkpoint inhibitors according …
K Khaddour, JM Kamel, N Meeder, X Ziqiao, C Sandra… - 2023 - ascopubs.org
e14696 Background: Immune checkpoint inhibitor (ICI) constitute the mainstay of therapy in
metastatic non-small cell lung cancer (NSCLC) and head and neck squamous cell cancer …
metastatic non-small cell lung cancer (NSCLC) and head and neck squamous cell cancer …
Parametric response mapping for the analysis of regional inflation in the prone position
Rationale: ventilator-induced lung stretch. In this study, we investigated the effects of prone
vs. supine position on the gravitational distributions of lung inflation using parametric …
vs. supine position on the gravitational distributions of lung inflation using parametric …