Childhood osteogenic sarcoma (OS) is a rare bone cancer occurring primarily in
adolescents. The North American pediatric cooperative groups have performed a series of …

Objectives: Access block refers to the delay caused for patients in gaining access to in-
patient beds after being admitted. It is almost always associated with emergency department …

Targeted therapies require cellular protein expression that meets specific requirements that
will maximize effectiveness, minimize off-target toxicities, and provide an opportunity for a …

The murine IgG3 monoclonal antibody (MoAb) 3F8, specific for the ganglioside GD2,
activates human complement, is active in antibody-dependent cellmediated cytotoxicity …

PURPOSE To test intensive alkylator-based therapy in desmoplastic small round-cell tumor
(DSRCT). PATIENTS AND METHODS Patients received the P6 protocol, which has seven …

Summary The ALK F1174L mutation is associated with intrinsic and acquired resistance to
crizotinib and cosegregates with MYCN in neuroblastoma. In this study, we generated a …

Large power penalties and bit-error-rate floors have been observed in some Gb/s systems
using distributed feedback (DFB) lasers, which could be attributed to interferometric …

PURPOSE To eradicate minimal residual disease with anti-G (D2) monoclonal antibody 3F8
in stage 4 neuroblastoma (NB) diagnosed at more than 1 year of age. PATIENTS AND …

Neuroblastoma is remarkable for its clinical heterogeneity and is characterized by genomic
alterations that are strongly correlated with tumor behavior. The specific genes that influence …

The spectrum of germline predisposition in pediatric cancer continues to be realized. Here
we report 751 patients with solid tumors who underwent prospective matched tumor–normal …