[HTML][HTML] Glucose metabolism in NSCLC is histology-specific and diverges the prognostic potential of 18FDG-PET for adenocarcinoma and squamous cell carcinoma

OCJ Schuurbiers, TWH Meijer, JHAM Kaanders… - Journal of thoracic …, 2014 - Elsevier
Introduction Biological features of non–small-cell lung carcinomas (NSCLCs) are important
determinants for prognosis. In this study, differences in glucose metabolism between adeno …

Differences in metabolism between adeno-and squamous cell non-small cell lung carcinomas: spatial distribution and prognostic value of GLUT1 and MCT4

TWH Meijer, OCJ Schuurbiers, JHAM Kaanders… - Lung cancer, 2012 - Elsevier
BACKGROUND: Hypoxia leads to changes in tumor cell metabolism such as increased
glycolysis. In this study, we examined the spatial distribution of the glycolysis and hypoxia …

[HTML][HTML] A brief retrospective report on the feasibility of epidermal growth factor receptor and KRAS mutation analysis in transesophageal ultrasound-and …

OCJ Schuurbiers, MG Looijen-Salamon… - Journal of Thoracic …, 2010 - Elsevier
Introduction: Molecular testing for epidermal growth factor receptor (EGFR) and KRAS
mutations is of increasing clinical importance in daily practice. In this study, we aimed to …

[HTML][HTML] Clinical outcomes and molecular profiling of advanced metastatic castration-resistant prostate cancer patients treated with 225Ac-PSMA-617 targeted alpha …

MJ van der Doelen, N Mehra, IM van Oort… - … Oncology: Seminars and …, 2021 - Elsevier
Introduction Targeted alpha-radiation therapy (TAT) with 225 Ac-labeled prostate-specific
membrane antigen (PSMA) ligands is a promising novel treatment option for metastatic …

[HTML][HTML] The role of 18F-FDG PET in the differentiation between lung metastases and synchronous second primary lung tumours

BG Dijkman, OCJ Schuurbiers, D Vriens… - European journal of …, 2010 - Springer
Purpose In lung cancer patients with multiple lesions, the differentiation between metastases
and second primary tumours has significant therapeutic and prognostic implications. The …

Timeliness of lung cancer diagnosis and treatment in a rapid outpatient diagnostic program with combined 18FDG-PET and contrast enhanced CT scanning

P Brocken, BAB Kiers, MG Looijen-Salamon… - Lung cancer, 2012 - Elsevier
INTRODUCTION: Delays in the diagnosis of lung cancer are under debate and may affect
outcome. The objectives of this study were to compare various delays in a rapid outpatient …

Glucose and glutamine metabolism in relation to mutational status in NSCLC histological subtypes

TWH Meijer, MG Looijen‐Salamon, J Lok… - Thoracic …, 2019 - Wiley Online Library
Background Both hypoxia and oncogenic mutations rewire tumor metabolism. In this study,
glucose and glutamine metabolism‐related markers were examined in stage I‐resectable …

Tumor delineation and quantitative assessment of glucose metabolic rate within histologic subtypes of non–small cell lung cancer by using dynamic 18f …

TWH Meijer, LF de Geus-Oei, EP Visser, WJG Oyen… - Radiology, 2017 - pubs.rsna.org
Purpose To assess whether dynamic fluorine 18 (18F) fluorodeoxyglucose (FDG) positron
emission tomography (PET) has added value over static 18F-FDG PET for tumor delineation …

Differences in screening history, tumour characteristics and survival between women with screen-detected versus not screen-detected cervical cancer in the east of …

MA van der Aa, EMJ Schutter… - European Journal of …, 2008 - Elsevier
OBJECTIVE: In The Netherlands, despite a national screening programme since 1996,
invasive cervical cancers have been detected in screened and non-screened women. The …

[HTML][HTML] Comparing deep learning and pathologist quantification of cell-level PD-L1 expression in non-small cell lung cancer whole-slide images

L van Eekelen, J Spronck, M Looijen-Salamon… - Scientific Reports, 2024 - nature.com
Abstract Programmed death-ligand 1 (PD-L1) expression is currently used in the clinic to
assess eligibility for immune-checkpoint inhibitors via the tumor proportion score (TPS), but …