Background FEV 1 is regarded as the most significant correlate of survival in COPD and is
used as a measure of disease severity in the staging of COPD. Recently, however, the …

Chronic obstructive pulmonary disease (COPD) is characterized by the presence of airflow
obstruction caused by emphysema or airway narrowing, or both. Low attenuation areas …

In this study, we analyzed the relationships of exercise capacity and health status to mortality
in patients with chronic obstructive pulmonary disease (COPD). We recruited 150 male …

When dyspnea must be assessed clinically, there are three methods of assessment: the
measurement of dyspnea with activities of daily living using clinical dyspnea ratings such as …

Three disease-specific, health-related quality of life (HRQL) questionnaires have been
introduced to assess patients with chronic obstructive pulmonary disease (COPD): the St …

Study objectives To compare categorizations of the level of dyspnea with the staging of
disease severity as defined by the FEV 1 in representing how the health-related quality of …

The purpose of the present study was to compare the characteristics of three different
exercise tests in evaluating the effects of oxitropium bromide on exercise performance. Thirty …

Rationale: Matrix metalloproteinase 9 (MMP-9) has proteolytic activity against connective
tissue proteins and appears to play an important role in the development of chronic …

Background: Chronic obstructive pulmonary disease (COPD) is characterised by the
presence of airflow limitation caused by loss of lung elasticity and/or airway narrowing. The …

Goals of effective management of patients with chronic obstructive pulmonary disease
(COPD) include relieving their symptoms and improving their health status. We examined …