[HTML][HTML] Genetic profiles of 103,106 individuals in the Taiwan Biobank provide insights into the health and history of Han Chinese

CY Wei, JH Yang, EC Yeh, MF Tsai, HJ Kao… - NPJ genomic …, 2021 - nature.com
Personalized medical care focuses on prediction of disease risk and response to
medications. To build the risk models, access to both large-scale genomic resources and …

[PDF][PDF] Taiwan Biobank: A rich biomedical research database of the Taiwanese population

YCA Feng, CY Chen, TT Chen, PH Kuo, YH Hsu… - Cell Genomics, 2022 - cell.com
Summary The Taiwan Biobank (TWB) is an ongoing prospective study of> 150,000
individuals aged 20–70 in Taiwan. A comprehensive list of phenotypes was collected for …

Neutrophil extracellular trap production and CCL4L2 expression influence corticosteroid response in asthma

CH Tsai, ACY Lai, YC Lin, PY Chi, YC Chen… - Science Translational …, 2023 - science.org
The association between neutrophil extracellular traps (NETs) and response to inhaled
corticosteroids (ICS) in asthma is unclear. To better understand this relationship, we …

[HTML][HTML] Gene-gene and gene-environmental interactions of childhood asthma: a multifactor dimension reduction approach

MW Su, KY Tung, PH Liang, CH Tsai, NW Kuo, YL Lee - PloS one, 2012 - journals.plos.org
Background The importance of gene-gene and gene-environment interactions on asthma is
well documented in literature, but a systematic analysis on the interaction between various …

Associations of serum perfluoroalkyl acid levels with T-helper cell-specific cytokines in children: By gender and asthma status

Y Zhu, XD Qin, XW Zeng, G Paul, L Morawska… - Science of the Total …, 2016 - Elsevier
Perfluoroalkyl acids (PFAAs) are a group of common chemicals that ubiquitously exist in
wildlife and humans. Experimental data suggest that they may alter T-lymphocyte …

[HTML][HTML] miR-200c and GATA binding protein 4 regulate human embryonic stem cell renewal and differentiation

HN Huang, SY Chen, SM Hwang, CC Yu, MW Su… - Stem cell …, 2014 - Elsevier
Human embryonic stem cells (hESCs) are functionally unique for their self-renewal ability
and pluripotency, but the molecular mechanisms giving rise to these properties are not fully …

[HTML][HTML] The role of interleukin-33 in patients with mild cognitive impairment and Alzheimer's disease

CS Liang, KP Su, CL Tsai, JT Lee, CS Chu… - Alzheimer's Research & …, 2020 - Springer
Background The neuroprotective role of interleukin (IL)-33 is supported by numerous
preclinical studies, but it remains uninvestigated in clinical studies of Alzheimer's disease …

Lipid profiles in children with and without asthma: interaction of asthma and obesity on hyperlipidemia

YC Chen, KY Tung, CH Tsai, MW Su, PC Wang… - Diabetes & Metabolic …, 2013 - Elsevier
AIMS: The joint effect of obesity and asthma on hyperlipidemia has never been explored. We
aim to examine (1) the association of dyslipidemia and asthma,(2) the interaction effect of …

[HTML][HTML] Associations between plasma biomarkers and cognition in patients with Alzheimer's disease and amnestic mild cognitive impairment: a cross-sectional and …

CL Tsai, CS Liang, JT Lee, MW Su, CC Lin… - Journal of Clinical …, 2019 - mdpi.com
Brain degeneration in patients with Alzheimer's disease (AD) results from the accumulation
of pathological amyloid-β (Aβ) plaques and tau protein tangles, leading to altered plasma …

Investigating obesity‐related risk factors for childhood asthma

YC Chen, MW Su, BM Brumpton… - Pediatric Allergy and …, 2022 - Wiley Online Library
Background We tested the hypothesis that multiple obesity‐related risk factors (obesity,
physical activity, cardiopulmonary physical fitness, sleep‐disorder breathing (SDB), and …