Background A review of studies on the association between childhood asthma and
socioeconomic status (SES) in industrialized countries leads to the conclusion that there …

Eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation
of inflammatory responses and thus have important roles in the pathogenesis of …

Background A close relation between asthma and allergic rhinitis has been reported by
several epidemiological and clinical studies. However, the nature of this relation remains …

Many" complex" human diseases, which involve multiple genetic and environmental
determinants, have increased in incidence during the past 2 decades. During the same time …

Background Asthma and allergy are complex multifactorial disorders, with both genetic and
environmental components determining disease expression. The use of molecular genetics …

Background: Early life development may influence subsequent respiratory morbidity. The
impact of factors determined in childhood on adult lung function, decline in lung function and …

OBJECTIVES--To examine whether road traffic in a big city has a direct effect on pulmonary
function and respiratory symptoms in children. DESIGN--Cross sectional study. SETTING--Of …

Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …

Allergen‐induced secretion of Th2‐type cytokines and IgE production have recently been
reported to be increased in mice treated with 1, 25 (OH) 2D, the active form of vitamin D. Our …

Rationale: Few studies have investigated the factors associated with the early inception of
chronic obstructive pulmonary disease (COPD). Objectives: We investigated COPD risk …