European position statement on lung cancer screening

M Oudkerk, A Devaraj, R Vliegenthart… - The Lancet …, 2017 - thelancet.com
Lung cancer screening with low-dose CT can save lives. This European Union (EU) position
statement presents the available evidence and the major issues that need to be addressed …

Lung cancer LDCT screening and mortality reduction—evidence, pitfalls and future perspectives

M Oudkerk, SY Liu, MA Heuvelmans… - Nature reviews Clinical …, 2021 - nature.com
In the past decade, the introduction of molecularly targeted agents and immune-checkpoint
inhibitors has led to improved survival outcomes for patients with advanced-stage lung …

[HTML][HTML] Reduced lung-cancer mortality with volume CT screening in a randomized trial

HJ de Koning, CM van Der Aalst… - New England journal …, 2020 - Mass Medical Soc
Background There are limited data from randomized trials regarding whether volume-based,
low-dose computed tomographic (CT) screening can reduce lung-cancer mortality among …

Lung cancer probability in patients with CT-detected pulmonary nodules: a prespecified analysis of data from the NELSON trial of low-dose CT screening

N Horeweg, J van Rosmalen, MA Heuvelmans… - The Lancet …, 2014 - thelancet.com
Background The main challenge in CT screening for lung cancer is the high prevalence of
pulmonary nodules and the relatively low incidence of lung cancer. Management protocols …

Low‐dose computed tomography lung cancer screening: Clinical evidence and implementation research

HL Lancaster, MA Heuvelmans… - Journal of Internal …, 2022 - Wiley Online Library
Lung cancer causes more deaths than breast, cervical, and colorectal cancer combined.
Nevertheless, population‐based lung cancer screening is still not considered standard …

Detection of lung cancer through low-dose CT screening (NELSON): a prespecified analysis of screening test performance and interval cancers

N Horeweg, ET Scholten, PA de Jong… - The Lancet …, 2014 - thelancet.com
Background Low-dose CT screening is recommended for individuals at high risk of
developing lung cancer. However, CT screening does not detect all lung cancers: some …

Occurrence and lung cancer probability of new solid nodules at incidence screening with low-dose CT: analysis of data from the randomised, controlled NELSON trial

JE Walter, MA Heuvelmans, PA de Jong… - The Lancet …, 2016 - thelancet.com
Background US guidelines now recommend lung cancer screening with low-dose CT for
high-risk individuals. Reports of new nodules after baseline screening have been scarce …

[HTML][HTML] Lung cancer prediction by Deep Learning to identify benign lung nodules

MA Heuvelmans, PMA van Ooijen, S Ather, CF Silva… - Lung cancer, 2021 - Elsevier
Abstract Introduction Deep Learning has been proposed as promising tool to classify
malignant nodules. Our aim was to retrospectively validate our Lung Cancer Prediction …

Optimisation of volume-doubling time cutoff for fast-growing lung nodules in CT lung cancer screening reduces false-positive referrals

MA Heuvelmans, M Oudkerk, GH de Bock… - European …, 2013 - Springer
Objective To retrospectively investigate whether optimisation of volume-doubling time (VDT)
cutoff for fast-growing nodules in lung cancer screening can reduce false-positive referrals …

[HTML][HTML] Relationship between nodule count and lung cancer probability in baseline CT lung cancer screening: The NELSON study

MA Heuvelmans, JE Walter, RB Peters, GH de Bock… - Lung Cancer, 2017 - Elsevier
Objectives To explore the relationship between nodule count and lung cancer probability in
baseline low-dose CT lung cancer screening. Materials and Methods Included were …