User profiles for "author:M G Semple"
 | Malcolm G SempleProfessor of Child Health and Outbreak Medicine, University of Liverpool Verified email at liverpool.ac.uk Cited by 35259 |
[HTML][HTML] A national consensus management pathway for paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS): results of a …
Paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-
TS) is a novel condition that was first reported in April, 2020. We aimed to develop a national …
TS) is a novel condition that was first reported in April, 2020. We aimed to develop a national …
[PDF][PDF] SARS-CoV-2 Omicron-B. 1.1. 529 leads to widespread escape from neutralizing antibody responses
On 24 th November 2021, the sequence of a new SARS-CoV-2 viral isolate Omicron-B. 1.1.
529 was announced, containing far more mutations in Spike (S) than previously reported …
529 was announced, containing far more mutations in Spike (S) than previously reported …
[HTML][HTML] Clinical features and management of human monkeypox: a retrospective observational study in the UK
H Adler, S Gould, P Hine, LB Snell, W Wong… - The Lancet Infectious …, 2022 - thelancet.com
Background Cases of human monkeypox are rarely seen outside of west and central Africa.
There are few data regarding viral kinetics or the duration of viral shedding and no licensed …
There are few data regarding viral kinetics or the duration of viral shedding and no licensed …
Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study
Objective To characterise the clinical features of patients admitted to hospital with
coronavirus disease 2019 (covid-19) in the United Kingdom during the growth phase of the …
coronavirus disease 2019 (covid-19) in the United Kingdom during the growth phase of the …
[HTML][HTML] Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19
Y Peng, AJ Mentzer, G Liu, X Yao, Z Yin, D Dong… - Nature …, 2020 - nature.com
The development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
vaccines and therapeutics will depend on understanding viral immunity. We studied T cell …
vaccines and therapeutics will depend on understanding viral immunity. We studied T cell …
Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C …
Objective To develop and validate a pragmatic risk score to predict mortality in patients
admitted to hospital with coronavirus disease 2019 (covid-19). Design Prospective …
admitted to hospital with coronavirus disease 2019 (covid-19). Design Prospective …
[HTML][HTML] Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study
RA Evans, H McAuley, EM Harrison… - The Lancet …, 2021 - thelancet.com
Background The impact of COVID-19 on physical and mental health and employment after
hospitalisation with acute disease is not well understood. The aim of this study was to …
hospitalisation with acute disease is not well understood. The aim of this study was to …
[HTML][HTML] Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults
B Killingley, AJ Mann, M Kalinova, A Boyers… - Nature Medicine, 2022 - nature.com
Since its emergence in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) has caused hundreds of millions of cases and continues to circulate globally. To establish …
2) has caused hundreds of millions of cases and continues to circulate globally. To establish …
Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study
Objective To characterise the clinical features of children and young people admitted to
hospital with laboratory confirmed severe acute respiratory syndrome coronavirus 2 (SARS …
hospital with laboratory confirmed severe acute respiratory syndrome coronavirus 2 (SARS …
[HTML][HTML] Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP …
Background Microbiological characterisation of co-infections and secondary infections in
patients with COVID-19 is lacking, and antimicrobial use is high. We aimed to describe …
patients with COVID-19 is lacking, and antimicrobial use is high. We aimed to describe …