Large Genomic Rearrangements in the Hepatocyte Nuclear Factor-1β (TCF2) Gene Are the Most Frequent Cause of Maturity-Onset Diabetes of the Young Type 5
…, S Clauin, D Chauveau, P Collin, M Daumont… - Diabetes, 2005 - Am Diabetes Assoc
Maturity-onset diabetes of the young (MODY) 5 is caused by mutations in the TCF2 gene
encoding the transcription factor hepatocyte nuclear factor-1β. However, in 60% of the …
encoding the transcription factor hepatocyte nuclear factor-1β. However, in 60% of the …
[HTML][HTML] The predictive and prognostic nature of programmed death-ligand 1 in malignant pleural mesothelioma: a systematic literature review
AS Mansfield, RJ Brown, C Sammon… - JTO Clinical and …, 2022 - Elsevier
Introduction Given the emergence of combination of programmed cell death protein-1 and
CTLA4 pathway blockade as effective treatment options in malignant pleural mesothelioma …
CTLA4 pathway blockade as effective treatment options in malignant pleural mesothelioma …
[HTML][HTML] First-line nivolumab plus ipilimumab versus chemotherapy for the treatment of unresectable malignant pleural mesothelioma: patient-reported outcomes in …
Abstract Objective In CheckMate 743 (NCT02899299), nivolumab+ ipilimumab significantly
prolonged overall survival in patients with unresectable malignant pleural mesothelioma …
prolonged overall survival in patients with unresectable malignant pleural mesothelioma …
Effectiveness and safety of nivolumab in the treatment of lung cancer patients in France: preliminary results from the real-world EVIDENS study
…, P Lamoureux, FE Cotte, V Allan, M Daumont… - …, 2020 - Taylor & Francis
ABSTRACT EVIDENS is an ongoing, prospective, non-interventional study evaluating the
effectiveness and safety of nivolumab in lung cancer patients in France (ClinicalTrials. gov …
effectiveness and safety of nivolumab in lung cancer patients in France (ClinicalTrials. gov …
[HTML][HTML] Trends in treatment patterns and survival outcomes in advanced non-small cell lung cancer: a Canadian population-based real-world analysis
Background As part of the multi-country IO Optimise research initiative, this population-
based study evaluated real-world treatment patterns and overall survival (OS) in patients …
based study evaluated real-world treatment patterns and overall survival (OS) in patients …
[HTML][HTML] Real-world treatment patterns and survival outcomes for advanced non-small cell lung cancer in the pre-immunotherapy era in Portugal: a retrospective …
…, R Munro, C Chaib, L Lacoin, M Daumont… - BMC Pulmonary …, 2020 - Springer
Background As part of the multinational IO Optimise research initiative, this retrospective
cohort study of patients with advanced non-small cell lung cancer (NSCLC) evaluated real …
cohort study of patients with advanced non-small cell lung cancer (NSCLC) evaluated real …
[HTML][HTML] Treatment patterns and outcomes for patients with malignant pleural mesothelioma in England in 2013–2017: A nationwide CAS registry analysis from the IO …
Objectives Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer with a
poor prognosis and limited treatment options. This study assessed the characteristics …
poor prognosis and limited treatment options. This study assessed the characteristics …
IO Optimise: a novel multinational real-world research platform in thoracic malignancies
…, JC O'donnell, JR Penrod, M Daumont… - Future …, 2019 - Future Medicine
Aim: To describe IO Optimise, a multinational program providing real-world insights into lung
cancer management. Materials & methods: Real-world data source selection for IO Optimise …
cancer management. Materials & methods: Real-world data source selection for IO Optimise …
Treatment patterns and survival outcomes for patients with non-small cell lung cancer in the UK in the preimmunology era: a REAL-Oncology database analysis from …
M Snee, S Cheeseman, M Thompson, M Riaz… - BMJ open, 2021 - bmjopen.bmj.com
Objectives To report characteristics, treatment and overall survival (OS) trends, by stage and
pathology, of patients diagnosed with non-small cell lung cancer (NSCLC) at Leeds …
pathology, of patients diagnosed with non-small cell lung cancer (NSCLC) at Leeds …
Artificial chemical and magnetic structure at the domain walls of an epitaxial oxide
Progress in nanotechnology requires new approaches to materials synthesis that make it
possible to control material functionality down to the smallest scales. An objective of …
possible to control material functionality down to the smallest scales. An objective of …