Criteria and definitions for the radiological and clinical diagnosis of bronchiectasis in adults for use in clinical trials: international consensus recommendations
S Aliberti, PC Goeminne, AE O'Donnell… - The Lancet …, 2022 - thelancet.com
Bronchiectasis refers to both a clinical disease and a radiological appearance that has
multiple causes and can be associated with a range of conditions. Disease heterogeneity …
multiple causes and can be associated with a range of conditions. Disease heterogeneity …
DYX1C1 is required for axonemal dynein assembly and ciliary motility
DYX1C1 has been associated with dyslexia and neuronal migration in the developing
neocortex. Unexpectedly, we found that deleting exons 2–4 of Dyx1c1 in mice caused a …
neocortex. Unexpectedly, we found that deleting exons 2–4 of Dyx1c1 in mice caused a …
[PDF][PDF] ZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6
MA Zariwala, HY Gee, M Kurkowiak… - The American Journal of …, 2013 - cell.com
Defects of motile cilia cause primary ciliary dyskinesia (PCD), characterized by recurrent
respiratory infections and male infertility. Using whole-exome resequencing and high …
respiratory infections and male infertility. Using whole-exome resequencing and high …
[PDF][PDF] The global burden of respiratory infections in indigenous children and adults: a review
TL Basnayake, LC Morgan, AB Chang - Respirology, 2017 - academia.edu
This review article focuses on common lower respiratory infections (LRIs) in indigenous
populations in both developed and developing countries, where data is available …
populations in both developed and developing countries, where data is available …
[PDF][PDF] ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry
The motive forces for ciliary movement are generated by large multiprotein complexes
referred to as outer dynein arms (ODAs), which are preassembled in the cytoplasm prior to …
referred to as outer dynein arms (ODAs), which are preassembled in the cytoplasm prior to …
Mutations of DNAI1 in Primary Ciliary Dyskinesia: Evidence of Founder Effect in a Common Mutation
MA Zariwala, MW Leigh, F Ceppa… - American journal of …, 2006 - atsjournals.org
Rationale: Primary ciliary dyskinesia (PCD) is a rare, usually autosomal recessive, genetic
disorder characterized by ciliary dysfunction, sino-pulmonary disease, and situs inversus …
disorder characterized by ciliary dysfunction, sino-pulmonary disease, and situs inversus …
Combined Haemophilus influenzae respiratory infection and allergic airways disease drives chronic infection and features of neutrophilic asthma
AT Essilfie, JL Simpson, ML Dunkley, LC Morgan… - Thorax, 2012 - thorax.bmj.com
Background 20–30% of patients with asthma have neutrophilic airway inflammation and
reduced responsiveness to steroid therapy. They often have chronic airway bacterial …
reduced responsiveness to steroid therapy. They often have chronic airway bacterial …
[HTML][HTML] Australian adults with bronchiectasis: The first report from the Australian Bronchiectasis Registry
Background/objective: There are no large, multi-centre studies of Australians with
bronchiectasis. The Australian Bronchiectasis Registry (ABR) was established in 2015 to …
bronchiectasis. The Australian Bronchiectasis Registry (ABR) was established in 2015 to …
The impact of primary ciliary dyskinesia on the upper respiratory tract
LC Morgan, CS Birman - Paediatric respiratory reviews, 2016 - Elsevier
Summary Primary Ciliary Dyskinesia (PCD) is an autosomal recessive genetic condition
affecting the function of motile cilia. The upper respiratory tract is lined with ciliated …
affecting the function of motile cilia. The upper respiratory tract is lined with ciliated …
Presentation of primary ciliary dyskinesia in children: 30 years' experience
PH Hosie, DA Fitzgerald, A Jaffe… - … of paediatrics and …, 2015 - Wiley Online Library
Aim Primary ciliary dyskinesia (PCD) is a rare (1: 15 000) condition resulting in recurrent
suppurative respiratory tract infections, progressive lung damage and hearing impairment …
suppurative respiratory tract infections, progressive lung damage and hearing impairment …