User profiles for "author:L Southgate"

Laura Southgate

St George's, University of London
Verified email at sgul.ac.uk
Cited by 6132

A systematic review and meta-analysis of set-shifting ability in eating disorders

…, K Tchanturia, D Stahl, L Southgate… - Psychological …, 2007 - cambridge.org
BackgroundThe aim was to critically appraise and synthesize the literature relating to set-
shifting ability in eating disorders. PsycINFO, Medline, and Web of Science databases were …

Patient‐oriented learning: a review of the role of the patient in the education of medical students

…, TS Gupta, K Singh, L Southgate - Medical …, 2000 - Wiley Online Library
Aim To explore the contribution patients can make to medical education from both
theoretical and empirical perspectives, to describe a framework for reviewing and monitoring …

Molecular genetic framework underlying pulmonary arterial hypertension

L Southgate, RD Machado, S Gräf… - Nature Reviews …, 2020 - nature.com
Pulmonary arterial hypertension (PAH) is a rare, progressive disorder typified by occlusion
of the pulmonary arterioles owing to endothelial dysfunction and uncontrolled proliferation of …

Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension

…, AM Holmes, CM Treacy, NJ Doughty, L Southgate… - Circulation, 2010 - Am Heart Assoc
Background—Inflammation is a feature of pulmonary arterial hypertension (PAH), and
increased circulating levels of cytokines are reported in patients with PAH. However, to date …

The relationship between competence and performance: implications for assessing practice performance

JJ Rethans, JJ Norcini, M Baron‐Maldonado… - Medical …, 2002 - Wiley Online Library
Objective This paper aims to describe current views of the relationship between competence
and performance and to delineate some of the implications of the distinctions between the …

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

…, POS Tam, GJ Gudmundsdottir, L Southgate… - Nature …, 2010 - nature.com
We conducted a genome-wide association study for primary open-angle glaucoma (POAG)
in 1,263 affected individuals (cases) and 34,877 controls from Iceland. We identified a …

[HTML][HTML] Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

…, M Bleda, C Hadinnapola, L Southgate… - Nature …, 2018 - nature.com
Pulmonary arterial hypertension (PAH) is a rare disorder with a poor prognosis. Deleterious
variation within components of the transforming growth factor-β pathway, particularly the …

Health and population effects of rare gene knockouts in adult humans with related parents

…, K Paigen, CA Parisinos, E Sheridan, L Southgate… - Science, 2016 - science.org
Examining complete gene knockouts within a viable organism can inform on gene function.
We sequenced the exomes of 3222 British adults of Pakistani heritage with high parental …

Pulmonary arterial hypertension: a current perspective on established and emerging molecular genetic defects

RD Machado, L Southgate, CA Eichstaedt… - Human …, 2015 - Wiley Online Library
Pulmonary arterial hypertension (PAH) is an often fatal disorder resulting from several
causes including heterogeneous genetic defects. While mutations in the bone …

Molecular genetic characterization of SMAD signaling molecules in pulmonary arterial hypertension

…, KM Snape, TY Bradshaw, L Southgate… - Human …, 2011 - Wiley Online Library
Heterozygous germline mutations of BMPR2 contribute to familial clustering of pulmonary
arterial hypertension (PAH). To further explore the genetic basis of PAH in isolated cases …