User profiles for "author:Kian Fan Chung"

Kian Fan Chung

Imperial College London
Verified email at imperial.ac.uk
Cited by 100105

Prevalence, pathogenesis, and causes of chronic cough

KF Chung, ID Pavord - The Lancet, 2008 - thelancet.com
Cough is a reflex action of the respiratory tract that is used to clear the upper airways.
Chronic cough lasting for more than 8 weeks is common in the community. The causes …

Impact of air pollution on the burden of chronic respiratory diseases in China: time for urgent action

WJ Guan, XY Zheng, KF Chung, NS Zhong - The Lancet, 2016 - thelancet.com
In China, where air pollution has become a major threat to public health, public awareness
of the detrimental effects of air pollution on respiratory health is increasing—particularly in …

[HTML][HTML] Confronting COVID-19-associated cough and the post-COVID syndrome: role of viral neurotropism, neuroinflammation, and neuroimmune responses

WJ Song, CKM Hui, JH Hull, SS Birring… - The Lancet …, 2021 - thelancet.com
Cough is one of the most common presenting symptoms of COVID-19, along with fever and
loss of taste and smell. Cough can persist for weeks or months after SARS-CoV-2 infection …

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

KF Chung, SE Wenzel, JL Brozek… - European respiratory …, 2014 - Eur Respiratory Soc
Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society …

Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program

WC Moore, DA Meyers, SE Wenzel… - American journal of …, 2010 - atsjournals.org
Rationale: The Severe Asthma Research Program cohort includes subjects with persistent
asthma who have undergone detailed phenotypic characterization. Previous univariate …

Neutrophilic inflammation in severe persistent asthma

A Jatakanon, C Uasuf, W Maziak, SAM Lim… - American journal of …, 1999 - atsjournals.org
Airway inflammation in severe asthma is not well characterized but may involve neutrophils.
We have compared induced sputum profiles in patients with asthma of varying severity and …

[HTML][HTML] Respiratory effects of exposure to diesel traffic in persons with asthma

J McCreanor, P Cullinan… - … England Journal of …, 2007 - Mass Medical Soc
Background Air pollution from road traffic is a serious health hazard, and people with
preexisting respiratory disease may be at increased risk. We investigated the effects of short …

Characterization of the severe asthma phenotype by the national heart, lung, and blood institute's severe asthma research program

WC Moore, ER Bleecker, D Curran-Everett… - Journal of Allergy and …, 2007 - Elsevier
BACKGROUND: Severe asthma causes the majority of asthma morbidity. Understanding
mechanisms that contribute to the development of severe disease is important. OBJECTIVE …

Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma

J Bousquet, E Mantzouranis, AA Cruz… - Journal of Allergy and …, 2010 - Elsevier
Asthma is a global health problem affecting around 300 million individuals of all ages, ethnic
groups and countries. It is estimated that around 250,000 people die prematurely each year …

[HTML][HTML] Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

DG Torgerson, EJ Ampleford, GY Chiu… - Nature …, 2011 - ncbi.nlm.nih.gov
Asthma is a common disease with a complex risk architecture including both genetic and
environmental factors. We performed a meta-analysis of North American genome-wide …