[HTML][HTML] The role of periostin in tissue remodeling across health and disease

SJ Conway, K Izuhara, Y Kudo, J Litvin… - Cellular and Molecular …, 2014 - Springer
Periostin, also termed osteoblast-specific factor 2, is a matricellular protein with known
functions in osteology, tissue repair, oncology, cardiovascular and respiratory systems, and …

Allergen immunotherapy for allergic asthma: a systematic review and meta‐analysis

S Dhami, A Kakourou, F Asamoah, I Agache, S Lau… - Allergy, 2017 - Wiley Online Library
Background To inform the development of the European Academy of Allergy and Clinical
Immunology's (EAACI) Guidelines on Allergen Immunotherapy (AIT) for allergic asthma, we …

Atopy and asthma: genetic variants of IL-4 and IL-13 signalling

T Shirakawa, KA Deichmann, K Izuhara, XQ Mao… - Immunology today, 2000 - cell.com
Recent genetic and functional studies highlight the importance of IL-4/IL-13 signalling in the
development of asthma and atopy. Here, Taro Shirakawa and colleagues discuss genetic …

Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals

G Takayama, K Arima, T Kanaji, S Toda… - Journal of Allergy and …, 2006 - Elsevier
BACKGROUND: Subepithelial fibrosis is a cardinal feature of bronchial asthma. Collagen I,
III, and V; fibronectin; and tenascin-C are deposited in the lamina reticularis. Extensive …

Ile50Val variant of IL4Rα upregulates IgE synthesis and associates with atopic asthma

H Mitsuyasu, K Izuhara, XQ Mao, PS Gao, Y Arinobu… - Nature …, 1998 - nature.com
E (IgE) production and leads to the clinical disorders of asthma, eczema and rhinitis1.
Interleukin 4 (IL4) is a pleiotropic cytokine which plays a crucial role in IgE-dependent atopic …

[HTML][HTML] Periostin promotes chronic allergic inflammation in response to Th2 cytokines

M Masuoka, H Shiraishi, S Ohta… - The Journal of …, 2012 - Am Soc Clin Investig
Allergic inflammation triggered by exposure of an allergen frequently leads to the onset of
chronic inflammatory diseases such as atopic dermatitis (AD) and bronchial asthma. The …

EAACI Guidelines on Allergen Immunotherapy: House dust mite‐driven allergic asthma

I Agache, S Lau, CA Akdis, S Smolinska, M Bonini… - Allergy, 2019 - Wiley Online Library
Allergen immunotherapy (AIT) has been in use for the treatment of allergic disease for more
than 100 years. Asthma treatment relies mainly on corticosteroids and other controllers …

Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids

Y Kanemitsu, H Matsumoto, K Izuhara, Y Tohda… - Journal of allergy and …, 2013 - Elsevier
Background Periostin, an extracellular matrix protein, contributes to subepithelial thickening
in asthmatic airways, and its serum levels reflect airway eosinophilic inflammation. However …

Periostin, a matrix protein, is a novel biomarker for idiopathic interstitial pneumonias

M Okamoto, T Hoshino, Y Kitasato… - European …, 2011 - Eur Respiratory Soc
Idiopathic interstitial pneumonias (IIPs) are histopathologically classified into several types,
including usual interstitial pneumonia (UIP), nonspecific interstitial pneumonia (NSIP) and …

Analysis of novel disease-related genes in bronchial asthma

N Yuyama, DE Davies, M Akaiwa, K Matsui… - Cytokine, 2002 - Elsevier
Bronchial asthma is a complex disease characterized by airway inflammation involving
interleukin (IL)-4 and IL-13. We have applied microarray analyses to human bronchial …