Chronotherapy for hypertension in obstructive sleep apnoea (CHOSA): a randomised, double-blind, placebo-controlled crossover trial
Background Obstructive sleep apnoea (OSA) is an important cause of secondary
hypertension. Nocturnal hypertension is particularly prevalent in OSA and is a strong …
hypertension. Nocturnal hypertension is particularly prevalent in OSA and is a strong …
[HTML][HTML] Diurnal changes in central blood pressure and pulse pressure amplification in patients with obstructive sleep apnoea
Study objectives Recent evidence suggests that compared to peripheral blood pressure
(BP), central BP may be more strongly associated with target organ damage and …
(BP), central BP may be more strongly associated with target organ damage and …
CAT-248, an allogeneic CD70-directed CAR-NK cell therapy effectively controls CD70-positive tumor xenografts
B Hamza, E Choi, D Picarella, F Moore, A Nunez… - Cancer Research, 2023 - AACR
Abstract Engineered, off-the-shelf, allogeneic natural killer (NK) cell therapy is an attractive
approach for targeting solid tumors, given their emerging clinical safety, efficacy, and …
approach for targeting solid tumors, given their emerging clinical safety, efficacy, and …
The lipogenic regulator SREBP induces Transferrin in circulating melanoma cells, suppressing their susceptibility to ferroptosis
Circulating tumor cells (CTCs) are shed by cancers into the bloodstream, where a viable
subset overcomes oxidative stress to initiate metastatic outgrowth. Clonally derived cultured …
subset overcomes oxidative stress to initiate metastatic outgrowth. Clonally derived cultured …